铜催化烯烃的不对称加成硼化反应研究进展  

Development of Cu-Catalyzed Asymmetric Addition of Boron to Olefin

作　　者：刘媛媛[1] 张万斌[2] 

机构地区：[1]华东师范大学化学与分子工程学院,上海200241 [2]上海交通大学化学化工学院,上海200240

出　　处：《有机化学》2016年第10期2249-2271,共23页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21502052)资助项目~~

摘　　要：铜催化烯烃的不对称加成硼化是构建手性碳硼键的有效方法,成为近年来有机化学的研究热点之一.从烯烃底物类型及反应类型的角度出发,总结了铜催化的烯烃的不对称加成硼化反应的研究进展.介绍了硼氢化反应及其串联反应以及包含硼化的双官能团化反应,以及以上反应的机理及发展现状,并对今后铜催化烯烃的不对称加成硼化反应的发展方向进行了展望.The Cu-catalyzed asymmetric addition of borons to olefins is an efficient method to the construct chiral C-B bonds and has therefore gained much attention over recent years. This review describes recent research progress concerning Cu-catalyzed asymmetric additions of borons to olefins on the view of the types of olefin substrates and reactions. Such reactions include hydroborations, cascade reactions, difunctionalization reactions, and their associated mechanisms and developments. Additionally, research trends of this area are also discussed.

关 键 词：铜 烯烃 不对称催化 加成硼化 串联反应 

分 类 号：O621.251[理学—有机化学]