咖啡酸片治疗甲巯咪唑所致白细胞减少临床观察  被引量:2

Clinical Observation of Caffeic Acid Tablets in the Treatment of Leukocyte Reduction Caused by Methimazole

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作  者:朱耀国[1] 樊琳[1] 杨军红[1] 

机构地区:[1]中国人民解放军第四五七医院,湖北武汉430012

出  处:《中外医学研究》2016年第31期35-36,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘  要:目的:观察咖啡酸片治疗抗甲状腺药物甲巯咪唑引起的白细胞减少的临床疗效和安全性。方法:将应用甲巯咪唑引起的白细胞减少患者88例随机分为两组,治疗组44例给予咖啡酸片0.2 g/次,3次/d,对照组44例给予鲨肝醇片0.1 mg,3次/d,观察4周,比较两组患者治疗前后白细胞数变化、不良反应等情况。结果:治疗组显效15例,有效26例,总有效率为93.18%,明显优于对照组的75%,差异有统计学意义(P<0.05),且无明显药物不良反应。结论:咖啡酸片治疗甲巯咪唑引起的白细胞减少安全有效。Objective:To observe Caffeic Acid Tablets in the treatment of leukocyte reduction caused by Methimazole.Method:88 cases of patients with leukocyte reduction caused by Methimazole were randomly divided into two groups,the treatment group(44 cases) was treated with Caffeic Acid Tablets 0.2 g each time,3 times/d,44 cases in the control group were given Batilol Tablets 0.1 mg,3 times/d,all patients were observed for 4 weeks, the white blood cell count changes and adverse reaction situation of two groups before and after treatment were compared.Result: In the treatment group,15 cases were markedly effective, 26 cases were effective,the total effective rate was 93.18%,significantly better than the control group of 75%,the difference was statistically significant(P〈0.05),and there was no obvious adverse drug reactions.Conclusion: Caffeic Acid Tablets in the treatment of leukocyte reduction caused by Methimazole is safe and effective.

关 键 词:咖啡酸片 甲巯咪唑 白细胞减少 

分 类 号:R581.1[医药卫生—内分泌]

 

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