输血前实施不规则抗体检测的意义和价值分析  

Analysis of Significance and Value of the Detection of Irregular Antibodies Before Blood Transfusion

作　　者：毛建玉[1] 肖文海[1] 叶祖兴 

机构地区：[1]福建医科大学附属三明第一医院,福建三明365000

出　　处：《中外医学研究》2016年第31期52-53,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究输血前实施不规则抗体检测的意义和价值。方法:从2010年1月-2016年1月,笔者所在医院共有3498例病患需进行输血治疗,对所有患者输血前都给予不规则抗体检测,回顾性分析检测结果。结果:所有患者的结果表明,阳性者24例,其中男性阳性率为0.35%(6/1738),女性阳性率为1.02%(18/1760)。女性阳性率显著高于男性。18例女性阳性患者中,非孕妇占0.52%(5/970),孕妇占1.65%(13/790)。孕妇不规则抗体阳性率显著大于非孕妇,差异有统计学意义(P<0.05)。24例不规则抗体阳性患者中,抗-M占29.17%(7/24),抗-D占25.00%(6/24),抗-E占20.83%(5/24),抗-C占16.67%(4/24),非特异性抗体占8.33%(2/24)。结论:临床在对患者进行输血治疗前先实施不规则抗体检测有利于保证患者的输血安全,有效降低临床医疗事故。临床应加强孕产妇血液检测,有效控制新生儿出现溶血病。Objective：To study significance and value of the detection of irregular antibodies before blood transfusion. Method：From January 2010 to January 2016,in the author＇s hospital,a total of 3498 patients suffering from the need for blood transfusions were given irregular antibody screening of all patients before transfusion, the test results were analyzed retrospectively.Result：The results showed that all the patients,positive patients were a total of 24 cases,which male positive rate was 0.35%（6/1738）.The positive rate of female was 1.02%（18/1760）.The positive rate of female was significantly higher than that of male.In 18 women with positive,non pregnant women accounted for 0.52%（5/970）, pregnant women accounted for 1.65%（13/790） The positive rate of irregular antibody in pregnant women was significantly higher than that in non pregnant women,and the difference was statistically significant（P〈0.05）.Among 24 patients with irregular antibody positive,Anti-M was 29.17%（7/24）,Anti-D accounted for 25%（6/24）,Anti-E accounted for 20.83%（5/24）, Anti-C accounted for 16.67%（4/24）,nonspecific antibodies accounted for 8.33%（2/24）.Conclusion： Clinical implementation before giving blood transfusions in patients with irregular antibody testing can ensure the patient＇s blood transfusion safety,reduce clinical medical accidents.Clinical maternal blood tests should be strengthened,effectively control neonatal hemolytic disease.

关 键 词：输血 不规则抗体 检测 

分 类 号：R446.6[医药卫生—诊断学] R457.1[医药卫生—临床医学]