男男性行为艾滋病毒感染者梅毒感染的影响因素分析  

Influencing factors of syphilis in the ADIS patients of men who have sex with men

作　　者：高慧[1] 肖芙蓉[1] 许小珍[1] 林锋[1] 张秀春[1] 毛海燕[2] 

机构地区：[1]海南省人民医院感染科,海口570311 [2]海南省人民医院皮肤科,海口570311

出　　处：《中国性科学》2016年第10期91-95,共5页Chinese Journal of Human Sexuality

摘　　要：目的:了解男男性行为(MSM)艾滋病毒感染者之梅毒感染的影响因素,为医师制定合适的行为介入和卫教宣导干预方案提供指导。方法:本研究于2014年1月至2015年6月期间,以自填问卷的方式,对我院建档复诊的MSM艾滋病毒感染者进行问卷调查,问卷调查内容主要包括人口学基本资料、健康状况及服药情况、性行为模式三大部分。结果:263例MSM艾滋病毒感染者中,48.7%出现梅毒感染,单因素分析发现,职业、病程、CD4 T细胞数量、病毒载量、是否使用HAART药物、主要性伴侣是否为HIV感染者、是否有非主要性伴侣、有无使用娱乐性药物8个因素是艾滋病毒感染者之梅毒感染的相关变项。多因素分析发现,教师/军人/公职人员(OR=0.20)是梅毒感染的保护因素,使用HAART药物(OR=4.67)、主要性伴侣是/有的是有的不是HIV感染者(OR=3.41)、有非主要性伴侣(OR=2.19)以及使用娱乐性药物(OR=2.14)是梅毒感染的危险因素。结论:MSM艾滋病感染者之后感染梅毒的情况较为普遍,在后续的追踪管理中应结合危险因素加强对高危人员的行为介入和卫教宣导,减少其梅毒感染几率。Objectives： To understand the influencing factors of syphilis in the ADIS patients of men who have sex with men（ MSM）,and provide guidance for doctors in developing appropriate intervention program and health education advocacy. Methods： ADIS MSM patients in our hospital between January 2014 and June 2015 were selected to finish the questionnaire,which included three parts： basic demographic data,health status and medication,and behavior patterns. Results： In the 263 AIDS MSM patients,48. 7% of them had syphilis infection,and univariate analysis showed that occupation,duration,CD4 number,viral load,whether to use HAART drugs,main sexual partner having HIV infection or not,having non- primary sex partner or not,with or without the use of recreational drugs were related variables for syphilis infection of ADIS MSM patients. Multivariate analysis found that teachers / military / public officer（ OR = 0. 20） were protective factors for syphilis infection,using HAART medications（ OR = 4. 67）,the main partner being infected by HIV（ OR = 3. 41）,having non- primary sexual partner（ OR = 2. 19） and use of recreational drugs（ OR = 2. 14） were risk factors for syphilis infection.Conclusion： Syphilis infection is more common in the AIDS MSM patients. Risk factors for high- risk personnel should be considered in the follow up to strengthen the behavior intervention and health education advocacy,and reduce their chances of syphilis infection.

关 键 词：男男性行为 艾滋病 梅毒 性行为 

分 类 号：R759.1[医药卫生—皮肤病学与性病学] R512.91[医药卫生—临床医学]