无精子症患者血清抑制素B测定的临床意义  

The significance of detection of serum inhibin B in azoospermia

作　　者：李芃[1] 宋世威[1] 

机构地区：[1]沈阳东方医疗集团菁华医院男科,沈阳110005

出　　处：《中国性科学》2016年第10期105-106,共2页Chinese Journal of Human Sexuality

摘　　要：目的:通过对无精子症患者血清抑制素B(INH-B)水平的测定来鉴别梗阻性无精子症(OA)及非梗阻性无精子症(NOA),并对NOA患者睾丸切开取精及睾丸显微取精成功率进行预判。方法:对我中心就诊的3650例无精子症患者进行血清INH-B水平测定,分为OA组及NOA组。结果:OA组患者血清INH-B水平明显高于NOA组,NOA组中睾丸切开取精及睾丸显微取精获得精子者血清INH-B水平高于未获得精子者。结论:血清INH-B在鉴别OA与NOA以及判断NOA患者睾丸切开取精及睾丸显微取精成功方面是一个较好的临床测定指标。Objectives： To distinguish obstructive azoospermia（ OA） and non- obstructive azoospermia（ NOA） and evaluate the success rate of testicular sperm extraction through orchidotomy or microsurgery by detecting serum inhibin B（ INH- B） in azoospermia. Methods： The levels of INH- B were measured by ELISA in 3650 patients suffered with OA and NOA. Results： The level of INH- B in OA was significantly higher than that in NOA.The patients obtaining sperms successfully in testicular sperm extraction had higher level of INH- B than those failed. Conclusion： INH- B is an important marker not only to differentiate OA and NOA,but also to evaluate the success rate of testicular sperm extraction.

关 键 词：血清抑制素B 无精子症 

分 类 号：R698.2[医药卫生—泌尿科学]