不孕不育患者解脲支原体、沙眼衣原体及淋病奈瑟氏菌感染状况调查  

Correlation between ureaplasma urealyticum,chlamydia trachomatis,neisseria gonorrhoeae infection and infertility

作　　者：赵本书 牟玲[2] 

机构地区：[1]重庆协和医院不孕科,重庆400041 [2]中国人民解放军324医院妇产科,重庆400020

出　　处：《中国性科学》2016年第10期109-112,共4页Chinese Journal of Human Sexuality

摘　　要：目的:探讨解脲支原体、沙眼衣原体、淋病奈瑟氏菌感染与不孕不育的相关性。方法:选取2012年8月至2015年8月于我院诊治的不孕不育症患者800例纳入不孕不育组,另选取同期于我院健康体检或产检者800例纳入健康对照组。采用荧光定量PCR仪测定两组患者解脲支原体、沙眼衣原体及淋病奈瑟氏菌DNA。结果:与健康对照组相比,不孕不育组患者解脲支原体感染、沙眼衣原体感染、解脲、沙眼衣原体同时感染、淋病奈瑟氏菌感染率明显较高(P<0.05)。不孕不育组130对夫妻中丈夫和妻子的解脲支原体、沙眼支原体感染率分别为62.3%、59.2%、44.6%、39.2%,其夫妻间感染解脲支原体、沙眼支原体具有相关性(r=0.864,P<0.05;r=0.773,P<0.05)。结论:生殖道解脲支原体、沙眼衣原体、淋病奈瑟氏菌感染与不孕不育相关,有必要对不孕不育夫妻同时检测解脲支原体、沙眼衣原体、淋病奈瑟氏菌DNA。Objectives： To explore the correlation between ureaplasma urealyticum,chlamydia trachomatis,neisseria gonorrhoeae infection and infertility. Methods： 800 infertile patients in our hospital from August 2012 to August 2015 were selected into infertile group and 800 people of health examination or antenatal care over the same period were selected into healthy control group. Ureaplasma urealyticum,chlamydia trachomatis and neisseria gonorrhoeae DNA of patients were tested by fluorescent quantitative PCR. Results： Compared to healthy control group,patients in the infertile group had higher infection rate of ureaplasma urealyticum,chlamydia trachomatis,ureaplasma urealyticum and chlamydia trachomatis joint neisseria gonorrhoeae（ P〈 0. 05）. Infection rate of ureaplasma urealyticum and chlamydia trachomatis in 130 couples of infertile group were 62. 3%,59. 2%,44. 6%,39. 2%,and the infection of ureaplasma urealyticum,chlamydia trachomatis between husband and wife were correlated（ r =0. 864,P〈 0. 05; r = 0. 773,P〈 0. 05）. Conclusion： Ureaplasma urealyticum,chlamydia trachomatis and neisseria gonorrhoeae infection is correlated with infertility,therefore,it is necessary to test ureaplasma urealyticum,chlamydia trachomatis and neisseria gonorrhoeae DNA of infertile couples at the same time.

关 键 词：解脲支原体 沙眼衣原体 淋病奈瑟氏菌 不孕不育 相关性 

分 类 号：R711.6[医药卫生—妇产科学]