AMI患者院前延误时间分布及心肌梗死后不同时间段的预后分析  

Prognostic Analysis of Different Pre-hospital Delay Times and Time Distribution Segments after Myocardial Infarction

作　　者：朱灿 韦兵 孙磊 李俊 许凯 

机构地区：[1]解放军第一零五医院,安徽合肥230031

出　　处：《现代生物医学进展》2016年第28期5564-5566,共3页Progress in Modern Biomedicine

基　　金：卫生部医药卫生科技发展项目(W2013GJ09)

摘　　要：目的:分析急性心肌梗死(acute myocardial infarction,AMI)院前延误时间分布及心肌梗死后不同时间段的预后情况。方法:选取AMI患者共208例,分析不同院前延误时间(pre-hospital delay times,PDT)患者的治疗情况、心室纤颤发生率、复苏成功率和死亡率。采用Logistic回归分析,分析影响PDT的相关因素。结果:61 min-120 min溶栓治疗率最高,为87.04%;121 min-240 min PCI/CABG治疗率最高,为20.93%;>720min药物治疗率最高,为100%,但无显著差异(P>0.05)。其中药物治疗组的PDT为(323.86±23.07)min,显著高于PCI/CABG组(108.69±10.84)min和溶栓组(112.35±15.73)min,(P<0.05)。首诊医院、处理方式、感知严重性、夜间发病和PDT具有显著相关性(P<0.05)。PDT≤120min组的心室纤颤发生率为12.26%,显著高于PDT>12 min组(P<0.05)。结论:患者和家属应加强学习AMI相关知识,缩短PDT,尽早诊治,避免因心室纤颤导致的死亡。Objective： To analyze the pre-hospital delay time distribution and prognosis of acute myocardial infarction （AMI）. Methods： A total of 208 cases of AMI patients were treated in our department. According to different pre-hospital delay times （PDT） of patients, they were divided into different groups. The incidence of ventrieular fibrillation, resuscitation and mortality were compared. Logistic regression analysis was adopted for relevant factors of PDT. Results： The highest rate ofthrombolytic therapy was 87.04% for 61 min-120 min group. The highest rate ofPCI / CABG therapy was 20.93% for 121 min-240 min group. The highest rate of medications was 100% for 〉 720 min group, but there was no significant difference （P〉 0.05）. The PDT was （323.86 ± 23.07） rain in drug treatment group, which was significantly higher than （108.69 ±10.84） min in PCI/CABG group and （112.35 ± 15.73） rain in thrombolysis group （P 〈0.05）. First visit hospitals, treatment, perceived severity and night incidence has a significant correlation with PDT （P 〈0.05）. The ventricular fibrillation rate in FDT≤ 120 min group was 12.26%, which was significantly higher than PDT 〉 12 rain group （P 〈0.05）. Conclusions： Patients and their families should enhance learning AMI-related knowledge to shorten PDT for early diagnosis and treatment, avoiding death due to ventricular fibrillation.

关 键 词：急性心肌梗死 院前延误时间 预后 

分 类 号：R542.22[医药卫生—心血管疾病]