不同低氧暴露对大鼠血液血红蛋白和红细胞数量的影响  

Influence of Different Hypoxic Exposure on the Number of RBC and Hb in Rats

作　　者：高梦雅[1] 胡靖平[1] 张俊福[1] 

机构地区：[1]金华职业技术学院,浙江金华321007

出　　处：《金华职业技术学院学报》2016年第6期86-89,共4页Journal of Jinhua Polytechnic

摘　　要：目的:观察不同氧浓度对大鼠血液中血红蛋白和红细胞数量的影响。方法:5周龄健康雄性大鼠80只,随机分为11%和15%氧浓度干预组,分别包括常氧对照组(C11,C15),低氧处理组(4H11,4H15,8H11,8H15,12H11,12H15)。对照组正常饲养,低氧处理组每天分别在11%和15%氧浓度环境中暴露4小时、8小时和12小时,连续暴露7天。检测所有组大鼠的血液血红蛋白浓度、红细胞的数量。结果:11%氧浓度下,4H11组的红细胞数量显著高于8H11组(P<0.05),各组血红蛋白浓度无显著性差异;15%氧浓度下暴露各组红细胞数量和血红蛋白浓度无显著性变化。结论:11%氧浓度下分别暴露4、8、12小时,红细胞数量呈先下降后上升的趋势;15%氧浓度对红细胞数量无显著性变化。两种氧浓度下暴露4、8、12小时均不能对血红蛋白浓度产生影响。Objective： This paper aimed to observe and analyze the influence of different hypoxic exposure on the number of red blood cells and hemoglobin in young rats. Methods： 80 male SD rats were randomly assigned into control groups （C11, C15） and hypoxic treatment groups. According to different hypoxic exposure time （4,8,12 h/d） and oxygen concentration （11%, 15% ）, hypoxic treatment groups were divided （4H11, 4H15, 8H11, 8H15,12H11,12H15）and then detected the blood about red blood cells （RBC）, hemoglobin （Hb）. Results： The number of RBC of 8HH group was significantly lower than 4H11 groups （P〈0.05）. There is no significantly difference between every group in hemoglobin. Conclusion： Comparison with 8 h/d, seven consecutive days＇ 11% oxygen concentration hypoxic exposure for 4 h/d promotes the number of RBC in the blood. There is no influence on the number of hemoglobin in 11% oxygen concentration hypoxic exposure. There is no influence on the number of RBC and hemoglobin in 15% oxygen concentration hypoxic exposure.

关 键 词：低氧训练 红细胞 血红蛋白 

分 类 号：R331.141[医药卫生—人体生理学]