胸部专科医院铜绿假单胞菌耐药性分析  

Analysis of antimicrobial resistance of Pseudomonas aeruginosa in chest hospital

作　　者：王生伟[1] 施旭东[2] 

机构地区：[1]南京市胸科医院急诊科,江苏南京210029 [2]南京市胸科医院检验科,江苏南京210029

出　　处：《临床肺科杂志》2016年第12期2234-2237,共4页Journal of Clinical Pulmonary Medicine

摘　　要：目的铜绿假单胞菌是自然界较常见的条件致病菌之一,通过分析本院检验科铜绿假单胞菌培养阳性标本的药敏结果,了解胸部专科医院铜绿假单胞菌感染的特点。方法收集2013年1月至2015年12月南京市胸科医院检验科铜绿假单胞菌培养阳性的506份标本,进行药敏结果分析。结果专科医院铜绿假单胞菌对常用抗生素的耐药率与综合性医院基本接近,氨基糖甙类和氟喹诺酮类抗生素耐药率偏高;多耐药铜绿假单胞菌感染患者的炎性指标要显著高于非多耐药的患者,而在反映患者营养状况的指标方面,结果相反;两者在淋巴细胞亚群分析方面差异无显著性。结论铜绿假单胞菌耐药问题目前已经较为严重,多耐药患者的治疗难度大,需采用多种方法加以治疗、控制和预防。Objective To analyze the results of drug sensitivity of pseudomonas aeruginosa culture-positive speci- mens, in order to summarize the characteristics of pseudomooas aeruginosa infection in chest hospital. Methods Strains of P. aeruginosa isolating from January 2013 toDecember 2012 were collected. The results of drug sensitivity analysis were carried out in 506 samples with positive culture. Results The drug resistance rate of Pseudomonas aeruginosa in our hospital was close to the general hospital. Aminoglycosides and fluoroquinolones antibiotic resist- ance rate was higher than other hospitals. The inflammatory parameters in patients with muhi drug resistant Pseudo- monas aeruginosa infection were significantly higher than those in the patients with non multi-drug resistance. In terms of nutritional indicators, the result was opposite. There was no significant difference between the two groups in the a- nalysis of lymphocyte subsets. Conclusion The drug resistance of Pseudomonas aeruginosa has been more serious. The treatment of multi drug-resistant patients is difficult. Which needs to take a variety of methods to treat, control and prevent.

关 键 词：胸部专科医院 铜绿假单胞菌 耐药分析 

分 类 号：R446.5[医药卫生—诊断学]