组织多普勒成像对诊断左室舒张功能减低的意义  

Diagnostic Value of Tissue Doppler Imaging for Left Ventricular Diastolic Function

作　　者：李德义[1] 杨世莉[1] 陶茂 陈睿[1] 周钰雯 张光对 罗莉[1] 

机构地区：[1]重庆市綦江区人民医院超声科,重庆401420

出　　处：《医学临床研究》2016年第10期1905-1907,1910,共4页Journal of Clinical Research

摘　　要：[目的]探讨应用组织多普勒成像技术（tissue Doppler imaging，TDI）诊断左室舒张功能减低的临床意义。[方法]选取2015年3月至2015年5月本院收治的高血压患者100例，采用TDI检测高血压痛患者房室瓣环舒张早晚期运动速度（Ea、Aa）与Ea／Aa，常规超声心动图彩色多普勒血流显像（CDFI）检测二尖瓣舒张早晚期血流速度（E、A）与E／A。随机选取正常人志愿者组50例作为对照组进行相同指标测定。[结果]CDFI显示：治疗组弛张异常型舒张功能减弱（E／A〈1）和限制异常型舒张功能减弱患者（E／A≥2）的E／A（0．59±0．13、2．24±0．17）与对照组（1．23±0．11）间差异显著（P〈0．05）；假性正常化表现患者（E／A在1～2之间）各项指标（91．20±7．12cm／s、69．17±6．06cm／s、1．27±0．08）与对照组（85．90±9．21cm／s、67．78±8．77cm／s、1．23±0．11）差异无统计学意义（P〉0．05）。TDI检测：弛张异常型舒张功能减弱与假性正常化表现患者（Ea〈12cm／s、Ea／Aa〈1）的Ea／Aa（0．59±0．06、0．55±0．04）与对照组（1．38±0．07）差异显著（P〈0．05）；限制异常型舒张功能减弱患者（Ea〉Aa且均〈8cm／s）的Ea（4．01±0．31cm／s）和Aa（3．17±0．24cm／s）与对照组（15．12±0．87cm／s、10．12±0．53cm／s）差异显著（P〈0．05）。[结论]与CDFI比较，TDI技术检测高血压患者二尖瓣环运动频谱更为敏感，能够更准确的反应出二尖瓣环舒张期运动速度的改变，对左室舒张功能的诊断有重要意义。[Objective]To explore the value of tissue Doppler imaging（TDI）in diagnosing left ventricular diastolic function. [Methods]A total of 100 hypertensive patients in our hospital from March 2015 to June 2015 were selected as the study object. The early diastolic velocity （Ea）, late diastolic velocity （Aa） and Ea / Aa of hypertension patients were detected by TDI. The early diastolic flow velocity （E）, late diastolic velocity （A） and E/A were detected by color Doppler flow imaging （CDFI）. In addition, 50 healthy subjects were selected as the control group. [Results]CDFI results showed that the differences of E/A （0.59 ± 0.13） in abnormal relaxation type patients （E/A〈1） or E/A （2.24±0.17） in limited abnormal diastolic function declined type patients （E/A≥2）were statistically significant （P〈0.05） from E/A （1.23±0.11） in the control group . The difference of each index between pseudo-normalization （E/A1 - 2） patients （91.20 ± 7.12cm/s, 69.17 ± 6.06 cm/s,1.27±0.08） and the control group patients （85.90±9.21 cm/s,67.78±8.77 cm/s,1.23±0.11） was not significant （ P〉0.05）. TDI results showed that the differences in Ea/Aa of abnormal relaxation in diastolic function weakened type patients （0.59±0.06） and pseudo-normalization patients （0.55±0.04） had statistically significant （ P〈0.05） from the control group patients （1.38±0.07）.The differences in Ea and Aa of limited abnormal diastolic function declined type patients （4.01±0.31 cm/s,3.17±0.24 cm/s, respectively） and control group patients （15.12 ± 0.87 cm/s, 10.12 ± 0.53 cm/s, respectively） were statistically significant （ P 〈0.05）. [Conclusion]Compared to color Doppler flow imaging, TDI is more sensitive to the mitral annulus movement spectrum in patients with hypertension. It can more accurately reflect the changes of mitral annulus diastolic velocity, which is valuable in the evaluation of left ventricular diastolic function.

关 键 词：超声检查 多普勒 心室功能 左 心舒期 

分 类 号：R322.11[医药卫生—人体解剖和组织胚胎学]