参麦注射液治疗急性心肌梗死相关心力衰竭105例  

One Hundred and Five Cases of Related Heart Failure due to Acute Myocardial Infarction Treated with Ginseng and Radix Ophiopogonis Injection

作　　者：赵燕[1] 张毅刚[1] 王海波[1] 任淑红[1] 曹秋枚 蒋春英[1] 王森[1] 

机构地区：[1]徐州市中心医院,江苏徐州221009

出　　处：《河南中医》2016年第10期1730-1732,共3页Henan Traditional Chinese Medicine

基　　金：江苏省自然科学基金项目(编号:BK2007240)

摘　　要：目的:观察参麦注射液治疗急性心肌梗死(心梗)相关心力衰竭(心衰)的临床疗效。方法:选取本院2011年5月—2013年4月收治的急性心梗相关心衰患者210例作为研究对象,随机分为对照组与治疗组,每组各105例。对照组仅给予内科常规综合治疗及血运重建,治疗组在常规治疗及血运重建的基础上加用参麦注射液治疗。观察两组患者治疗前后左室射血分数(left ventricular ejection fraction,LVEF)、左室舒张末期内径(left ventricular end diastolic diameter,LVEDD)及血浆脑钠肽浓度((Brain Natriuretic Peptide,BNP)变化情况,比较两组患者心脏不良事件(MACE)发生情况。结果:两组患者治疗后BNP、LVEF、LVEDd均比治疗前有显著改善,且治疗组优于对照组,差异均有统计学意义(P<0.05)。治疗组MACE事件发生率显著低于对照组,差异有统计学意义(P<0.05)。治疗组有效率为93.33%,对照组有效率为77.14%,两组患者临床疗效比较,差异有统计学意义(P<0.05)。结论:参麦注射液能显著提高急性心肌梗死后心衰患者的远期临床疗效,且安全性好。Objective：To observe the clinical curative effect of Ginseng and Radix Ophiopogonis Injection on related heart failure due to acute myocardial infarction （AMI）. Methods：Two hundred and ten patients who were treated in our hospital between May of 2011 and April of 2013 were chosen as the research objects, and randomly divided into the control group and the treatment group, ,with 105 cases in each group, The ones in the control group were given routine comprehensive treatment of internal medicine and revascularization,while the ones in the treatment group were added Ginseng and Radix Ophiopogonis Injection based on the treatment of the control group. Then the two groups＇ left ventrieular ejection fraction （LVEF） ,left ventricular end diastolic diameter （LVEDD） and Brain Natriuretic Peptide （BNP）ehanges before and after the treatment were observed ,and the two groups＇ occurrences of MACE were compared. Results：After the treatment,the two groups＇ BNP,LVEF, LVEDD were all significantly improved ,and the treatment group was better than the control group;And all the differences between them had statistical significance （P 〈 0.05）. The occurrence of the treatment group was much lower than that of the control group; And the difference between them had statistical significance （ P 〈 0.05 ）. The effective rate of the treatment group was 93.33%, while that of the control group was 77.14% ;And the difference between them had statistical significance （P 〈0.05 ）. Conclusion：Ginseng and Radix Ophiopogonis Injection can greatly improve the long-time clinical curative effect on related heart failure due to acute myocardial infarction,and has good safety.

关 键 词：急性心肌梗死 心力衰竭 参麦注射液 

分 类 号：R542.22[医药卫生—心血管疾病]