α-烯醇化酶的研究进展  

Research advance of alpha-enolase

作　　者：张丽红[1] 王宏斌[1] 杨国灿[1] 董学君[1] 

机构地区：[1]浙江省绍兴市人民医院临床检验中心,312000

出　　处：《中华临床实验室管理电子杂志》2016年第2期91-94,共4页Chinese Journal of Clinical Laboratory Management(Electronic Edition）

基　　金：浙江省自然基因项目(LY14H200001);浙江省医药卫生平台重点资助课题(2013ZDA024);浙江省医药卫生平台计划项目资助课题(2015DTA018)

摘　　要：α-烯醇化酶(alpha-enolase,ENO1)在很长一段时间内被认为是一种古老的、功能单一的糖酵解酶。近年发现ENO1除了在糖酵解中发挥作用外,还具有多种生物学功能。目前研究主要集中在ENO1的免疫原性、纤溶酶原受体、肿瘤生长调控作用等方向,而与恶性肿瘤发生、发展的关系研究则备受关注。Alpha-enolase （ENO1） is considered to be a kind of old, single glycolytic enzyme in a long period. Recently, it is found that ENO1 has various biological functions in addition to glycolysis enzyme. Currently, the research of ENO1 mainly focuses on its role in immunogenicity, fibrinolytic enzyme receptor, tumor suppressor and promot or the relationship between ENO1 and malignant tumor became to be hot area.

关 键 词：α-烯醇化酶 肿瘤 免疫原性 纤溶酶原受体 

分 类 号：R446.1[医药卫生—诊断学]