不同含量的NBG对NBG/PLGA复合材料等温结晶、形貌和力学性能的影响  

Effect of different content of NBG on the isothermal crystallization,morphology and mechanical property of NBG/PLGA composites

作　　者：祁金 熊成东[1] 张丽芳[1] 

机构地区：[1]中国科学院成都有机化学研究所,四川成都610049 [2]中国科学院大学,北京100049

出　　处：《西北师范大学学报（自然科学版）》2016年第6期70-77,共8页Journal of Northwest Normal University(Natural Science)

基　　金：中国科学院"西部之光"重点基金资助项目

摘　　要：先采用碱性溶胶-凝胶法结合冷冻干燥技术制备纳米生物活性玻璃(NBG),再利用溶液共混的方法制备不同比例的纳米生物活性玻璃/聚丙交酯-乙交酯(NBG/PLGA)生物可降解复合材料(NBG含量为3%,5%,10%,20%及30%).利用FTIR,SEM和EDS分析NBG表面形貌、元素组成和NBG/PLGA复合材料断面形貌;DSC和SANS微机控制电子万能试验机分析不同含量的NBG对复合材料在不同温度下等温结晶行为和力学性能的影响.结果表明,碱性溶胶-凝胶法结合冷冻干燥技术成功获得了分散性良好的纳米生物活性玻璃粉末;与未添加NBG的PLGA相比,NBG作为异相成核剂,有效提高了PLGA复合材料结晶能力,复合材料结晶时间随NBG含量增加而缩短.Avrami方程可用于描述本研究中NBG/PLGA复合材料的等温结晶过程.复合材料拉伸强度和断裂伸长率随NBG含量的增加,先增强后降低,NBG的最佳添加量为10%,复合材料的拉伸强度和断裂伸长率分别比纯PLGA提高28.79%和56.09%.该生物复合材料有望用于骨修复材料.Nano-bioactive glasses（NBG）have been prepared by a quick alkali-mediated sol-gel method and freeze drying technique.And a serials of NBG/PLGA biodegradable composites with NBG of 3%,5%, 10%,20% and 30% in weight are prepared by solution mixing method.The NBG surface and element contents are investigated by FTIR, SEM/EDS. The crystallization behaviors, morphology and mechanical property of NBG/PLGA composites are investigated by DSC, SEM and electromechanical universal test for the first time,respectively.The results showed that well distributed NBG has been prepared by a quick alkali-mediated sol-gel method and combined freeze drying technology.The Avrami equation is suitable for describing the isothermal crystallization process of NBG/PLGA composites in this work,and with the addition of NBG, the crystallization rate of NBG/PLGA composites is enhanced. With the increase of NBG content, the tensile strength of the composites is first enhanced, thennbsp;decreased.Finally it is found that the addition content of 10% NBG to PLGA matrix is the most appropriate proportion, the tensile strength and elongation at break of NBG/PLGA composite are increased 28.79% and 56.09%,respectively.The study would be of guidence to select the suitable fileer to PLGA polymer in manufacturing bone repair materials in future.

关 键 词：纳米生物活性玻璃(NBG) 复合材料 结晶 形貌 力学性能 聚丙交酯-乙交酯(PLGA) 

分 类 号：TQ174[化学工程—陶瓷工业]