缺血性中风证候要素与子午流注时辰规律的研究  

The Study of the Relationship between the Syndrome Element and the Temporal Rhythm of Midnight-noon Ebb-flow in Patients of Ischemic Stroke

作　　者：祖建[1] 霍锐[1] 樊艺[1] 李莉[1] 周竞峥 钟骏慧[1] 

机构地区：[1]重庆市中医院,重庆400021

出　　处：《中国中医急症》2016年第11期2055-2057,2065,共4页Journal of Emergency in Traditional Chinese Medicine

基　　金：重庆市卫生和计生委中医药科技项目(ZY201402043)

摘　　要：目的研究缺血性中风发病的子午流注时辰规律以及证候要素特点,分析经脉气血流注与证候要素对缺血性中风发病时间的影响。方法收集重庆市中医院2015年2月至2016年5月收治的383例缺血性中风患者发病时的证候要素和发病时间,应用圆形分布法分析发病的时间规律,并计算发病高峰期,以是否为高峰期发病为因变量,证候要素为自变量进行二值多元Logistic回归分析,分析证候要素对发病时间的影响。结果根据子午流注纳甲法推算出缺血性中风发病时的值日经,经圆形分布统计分析,r值为0.018,经雷氏检验P>0.05,故缺血性中风发病无显著的值日经聚集趋势。分析子午流注纳子法时辰周期的发病规律发现,发病高峰为7时04分,发病高峰期为3时02分至11时06分,r值为0.5238,经雷氏检验P<0.05,即寅时至巳时为缺血性中风发病的高峰期。以是否为高峰期发病为因变量,证候要素为自变量进行二值多元Logistic回归分析,血瘀、痰湿、气虚为是否高峰期发病的主要影响因素,其OR值分别为:3.76,4.21,3.55。结论气血流经肺经、大肠经、胃经、脾经时为缺血性中风发病的高峰期,血瘀、痰湿、气虚证候要素为是否高峰期发病的主要影响因素。Objective： To research the relationship between the syndrome element and the temporal rhythm of midnight-noon ebb-flow in patients of ischemie stroke. Methods： 383 cases of isehemie stroke from February 2015-May 2016 in Chongqing Hospital of Traditional Chinese Medicine were collected. The data on the attack time and the syndrome element was reviewed. Circular distributive analysis was applied to research the temporal rhythm of midnight-noon ebb-flow and to figure out the peak duration. We took the syndrome element as the in- dependent variable and whether the attack happened in the peak duration as the dependent variable to make a multiple stepwise logistic regression analysis in order to explore the syndrome element influential factors on the attack time. Results： According to the Najia method of midnight,noon ebb-flow,there was no central trend ap- peared,the γ value was 0.018（P〉 0.05）. According to the Nazi method of midnight-noon ebb-flow,the peak time was 7：04 and the peak duration was from 3：02 to 11：06,the γ value was 0.5238 （P〈 0.05）. The peak incidence of ischemic stroke was from Yin Shi to Si Shi. We took the syndrome element as the independent variable and whether the attack happened in the peak duration as the dependent variable to make a multiple stepwise logistic regression analysis. Moreover,we took blood＇stasis,phtegm-dampness and qi deficiency as the main influence factors. The OR value were 3.76,4.21,3.55 respectively. Conclusion： The peak incidence of isehemic stroke is the time when the qi and blood disembogue Lung Meridian,Large Intestine Meridian,Stomach Meridian,Spleen Meridian. The main syndrome element influential factors of the attack time are blood stasis,phlegm dampness, qi deficiency,

关 键 词：缺血性中风 子午流注 圆分布统计 证候要素 LOGISTIC回归分析 

分 类 号：R255.2[医药卫生—中医内科学]