Evaluation of Myocardial Strain and Aortic Elasticity in Patients with Bicuspid Aortic Valve  

作　　者：李阳 邓又斌 毕小军 刘娅妮 张隽 李礼 陈斌 

机构地区：[1]Department of Medical Ultrasound, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030, China [2]Department of Medical Ultrasound, the First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China [3]Department of Medical Ultrasound, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China

出　　处：《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第5期747-751,共5页华中科技大学学报（医学英德文版）

基　　金：supported by the National Natural Science Foundation of China(No.81571695)

摘　　要：This study evaluated the myocardial strain and aortic elasticity in patients with bicuspid aortic valve（BAV） and then investigated the relation between them. Thirty-nine patients（30 males; mean age 44±19 years; range 6 to 75 years） with BAV were recruited as BAV group, and 29 age- and sex-matched healthy controls（21 males; mean age 42±11 years; range 20 to 71 years） served as control group. Aortic strain, distensibility and stiffness index were derived using M-mode echocardiography. Left ventricular global myocardial strain was acquired with speckle-tracking echocardiography. Correlation between aortic elasticity and myocardial strain was also analyzed. The results showed that aortic stiffness was higher（17.5±14.0 vs. 5.3±2.7, P〈0.001）, and aortic strain（4.9±4.7 vs. 11.0±4.1, P〈0.001） and distensibility（1.8±2.1 vs. 3.7±1.6, P〈0.001） were lower significantly in BAV group than in control group. Global circumferential strain（–19.1±4.2 vs. –22.5±3.7, P〈0.001）, radial stain（29.8±14.9 vs. 38.0±8.8, P〈0.001） and longitudinal stain（–18.4±3.4 vs. –20.8±3.5, P〈0.001） were significantly lower in BAV group than in control group. There was weak association between aortic elasticity and myocardial strain. These findings indicated BAV patients manifest reduced myocardial strain which had weak relationship with aortic elastic lesion.This study evaluated the myocardial strain and aortic elasticity in patients with bicuspid aortic valve（BAV） and then investigated the relation between them. Thirty-nine patients（30 males; mean age 44±19 years; range 6 to 75 years） with BAV were recruited as BAV group, and 29 age- and sex-matched healthy controls（21 males; mean age 42±11 years; range 20 to 71 years） served as control group. Aortic strain, distensibility and stiffness index were derived using M-mode echocardiography. Left ventricular global myocardial strain was acquired with speckle-tracking echocardiography. Correlation between aortic elasticity and myocardial strain was also analyzed. The results showed that aortic stiffness was higher（17.5±14.0 vs. 5.3±2.7, P〈0.001）, and aortic strain（4.9±4.7 vs. 11.0±4.1, P〈0.001） and distensibility（1.8±2.1 vs. 3.7±1.6, P〈0.001） were lower significantly in BAV group than in control group. Global circumferential strain（–19.1±4.2 vs. –22.5±3.7, P〈0.001）, radial stain（29.8±14.9 vs. 38.0±8.8, P〈0.001） and longitudinal stain（–18.4±3.4 vs. –20.8±3.5, P〈0.001） were significantly lower in BAV group than in control group. There was weak association between aortic elasticity and myocardial strain. These findings indicated BAV patients manifest reduced myocardial strain which had weak relationship with aortic elastic lesion.

关 键 词：elasticity longitudinal Strain speckle valve Correlation manifest stiffness regurgitation matched 

分 类 号：R542.5[医药卫生—心血管疾病]