禹白芷适宜干燥加工方式的优选研究  

Optimization of Suitable Drying Processing Methods of Angelica dahurica

作　　者：周冰[1] 刘培[1] 鲁学军[1] 钱大玮[1] 段金廒[1,2] ZHOU Bing LIU Pei LU Xue-jun QIAN Da-wei DUAN Jin-ao(Nanjing University of Chinese Medicine/Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/ National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medi- cine,Nanjing 210023 ,China State Key Laboratory Breeding Base of Dao-di Herbs, China Academy of Chinese Medical Sciences, Beijng 100700,China)

机构地区：[1]南京中医药大学/江苏省中药资源产业化过程协同创新中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心,江苏南京210023 [2]中国中医科学院道地药材国家重点实验室培育基地,北京100700

出　　处：《中药材》2016年第7期1509-1515,共7页Journal of Chinese Medicinal Materials

基　　金：国家科技支撑计划项目(2012BAI29B02);国家中医药局公益性行业科研专项(201407005);江苏高校优势学科建设工程资助项目(PAPD);江苏省"333高层次人才培养工程"项目

摘　　要：目的:通过功效成分与外观性状的综合评价,优选禹白芷药材的适宜产地干燥加工技术,为根类中药材的干燥加工提供示范。方法:采用晒干、阴干、热风干燥、中波红外干燥等19种方式对禹白芷进行干燥加工。HPLC-PAD法分析不同干燥方法加工的禹白芷中香豆素类化学成分含量;GC-MS法分析其挥发油组成,并采用内标法定量;采用综合评分法评价外观性状。结果:禹白芷药材中总香豆素含量晒干组高于阴干组,热风变温干燥组整体均较高,恒温干燥组干燥温度与香豆素类成分含量呈反比。挥发油类成分热风变温干燥组整体均较高,恒温干燥组干燥温度与挥发油类成分含量呈反比。外观评价结果表明,热风50℃干燥组最好,其次为晒干组、阴干组、中波红外50℃组。结论:综合考虑干燥时间、外观、功效成分含量,推荐禹白芷干燥加工使用热风干燥,设备为控温控湿热风干燥机,其适宜温度为50℃,排湿湿度为35%。该方法可为白芷等根类中药材的适宜干燥技术规范的形成提供参考。Objective： To optimize the suitable drying processing methods of the root of Angelica dahurica by the appearance and the content of active compounds. Methods： 19 methods including natural drying in the shade,natural drying in the sun,hot air drying,shortwave infrared radiation drying were studied. HPLC-PDA method was adopted to determine the contents of coumarin compounds. GC-MS with internal standard method was used to determine the content of volatile oil. The appearance of samples was evaluated by the method of composite scores. Results： The results of coumarins contents showed that the natural drying in the sun was higher than natural drying in the shade,variable-temperature drying was the best,and the temperature of constant temperature drying was inversely proportional to the contents of coumarins. The results of volatile oils contents showed that variable-temperature drying was the best,and the temperature of constant temperature drying was inversely proportional to the contents of volatile oils. The results of composite scores showed that hot air drying in 50 ℃ was the best,followed by natural drying in the sun,natural drying in the shade and shortwave infrared radiation drying in 50 ℃. Conclusion： Therefore,considering the drying time,the appearance,and the content of active compounds,the hot air drying method and hot air machine with temperature and humidity controlled was recommend. The suitable parameters for the machine were that the drying temperature was 50 ℃,and the humidity was 35%. The method could provide the reference for the drying technology standard of roots such as Angelica dahurica.

关 键 词：禹白芷 干燥加工 香豆素 挥发油 品质评价 

分 类 号：R283.3[医药卫生—中药学]