胺碘酮联合厄贝沙坦治疗阵发性房颤的疗效观察  

Curative effect of amiodarone combined with irbesartan in the treatment of paroxysmal atrial fibrillation

作　　者：王允[1] 韩震[1] 马雪兴 李渊[1] 

机构地区：[1]苏州市立医院北区心血管内科,江苏苏州215008

出　　处：《中国医药科学》2016年第17期66-68,141,共4页China Medicine And Pharmacy

摘　　要：目的 分析阵发性房颤实施胺碘酮联合厄贝沙坦疗法的效果。方法 从我院2012年4月~2016年2月收治的阵发性房颤患者中抽选实施胺碘酮疗法的40例作为对照组,实施胺碘酮联合厄贝沙坦疗法的40例作为试验组,统计两组患者疾病治疗后的效果。结果 试验组疾病缓解率为92.5%,对照组缓解率为75.0%,差异有统计学意义（P〈0.05）;试验组、对照组患者疾病治疗3、6个月后窦性心律维持率差异无统计学意义（P〉0.05）;治疗9、12个月后的窦性心律维持率差异有统计学意义（P〈0.05）;试验组患者治疗6、12个月后的左心房内径低于对照组,差异有统计学意义（P〈0.05）。结论 临床给予阵发性房颤患者胺碘酮、厄贝沙坦联合疗法作用突出,可改善病症,预防左心房内径扩大,增强总体效果,值得学习。Objective To explore the effect of amiodarone combined with irbesartan in the treatment of paroxysmal atrial fibrillation. Methods 40 cases of patients with paroxysmal atrial fibrillation treated with amiodarone in our hospital from April 2012 to February 2016 were selected as control group, and 40 cases of patients with paroxysmal atrial fibrillation treated with amiodarone combined with irbesartan were selected as experiment group. Effects after treatment of the two groups were statistical. Results The response of experiment group for disease rate was 92.5%, and the remission rate of control group was 75.0%. There was statistical difference, （P 〈 0.05）. There were no distinctions on sinus rhythm maintenance rate 3 months, 6 months after treatment between experiment group and control group （P 〉 0.05）. There were some distinctions on sinus rhythm maintenance rate 9 months after treatment and 12 months after the rate （P 〈 0.05）. Left atrial diameters of patients in experiment group were less than those of patients in control group 6 months and 12 months after treatment. There was statistical difference （P 〈 0.05）. Conclusion The clinical effect of amiodarone combined with irbesartan in treatment of patients with paroxysmal atrial fibrillation is outstanding. It can improve disease, prevent left atrial enlargement, and enhance the overall effect. It is worth learning.

关 键 词：胺碘酮 厄贝沙坦 阵发性房颤 临床疗效 

分 类 号：R541.7[医药卫生—心血管疾病]