派特灵治疗老年尖锐湿疣的临床观察  

Clinical observation of Paiteling in treatment of elderly patients with condyloma acuminatum

作　　者：李衡贵[1] 

机构地区：[1]内蒙古包钢医院皮肤性病科,内蒙古包头014010

出　　处：《中国现代医生》2016年第28期100-102,共3页China Modern Doctor

摘　　要：目的 观察中药制剂派特灵治疗老年尖锐湿疣的临床效果和安全性。方法 选择2012年1月～2015年10月我院皮肤性病科门诊72例老年尖锐湿疣患者,随机分为两组,每组36例,观察组采用派特灵治疗,对照组采用超脉冲CO2激光治疗,两组均随访6个月,观察临床效果和不良反应。结果 观察组36例患者中治愈32例,复发4例,治愈率88.9%（32/36）,复发率11.1%（4/36）。32例治愈患者中,13例涂药半个疗程后疣体脱落,15例用药1个疗程后疣体全部脱落,4例用药2个疗程后疣体脱落。观察组的治愈率显著高于对照组,观察组的复发率显著低于对照组,差异有统计学意义（P〈0.05）。所有患者均未出现心、肝、肾、神经系统等全身性不良反应,其中8例患者用药后局部黏膜出现红肿、糜烂,停药3～5 d后上述症状消失。对照组1例患者分2次治疗去除疣体;2例患者出现血压升高现象,1例出现心悸,予对症治疗缓解,可继续治疗;1例肛周合并糖尿病患者创面感染,愈合后可见明显瘢痕。结论 中药制剂派特灵治疗老年尖锐湿疣临床效果满意,方法简单,安全性好,值得临床应用。Objective To investigate the efficacy and safety of traditional Chinese medicine Paiteling in treatment of elderly patients with condyloma acuminatum. Methods From January 2012 to October 2015 in our hospital dermatology, 72 cases of elderly patients with condyloma acuminatum were divided into two groups, observation group was treated with Paiteling, the control group was treated with ultra pulsed CO2 laser treatment. The two groups were followed up for 6 months, the clinical effect and adverse reaction were compared. Results Observation group of 36 cases were cured in 32 cases, 4 cases of recurrence. The cure rate was 88.9%（32/36）, and the recurrence rate was 11.1%（4/36）. 32 cases were cured, 13 cases wart body falling after half a course of treatment, 15 cases wart body falling off after 1 course treat- ment, 4 cases wart body falling off after 2 courses of treatment. The cure rate of observation group was significantly higher than that of control group, the recurrence rate of observation group was significantly lower than that of control group, the difference was statistically significant （P〈0.05）. All patients did not appear heart, liver, kidney, nervous sys- tem and other systemic adverse reactions, in which 8 cases of patients with local mucosal swelling, erosion, the above symptoms disappeared after stopping 3-5 days. One patient in control group was divided into two treatments to remove the warts; two cases of patients with high blood pressure, one case had palpitation, symptomatic remission, continued treatment; one case of perianal wound infection in patients with diabetes complicated with obvious scar after healing. Conclusion Paiteling in treatment of senile condyloma acuminatum has satisfactory effect, simple method, has good safety, and is worthy of clinical application.

关 键 词：尖锐湿疣 派特灵 老年患者 不良反应 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]