疏风解毒胶囊联合利巴韦林治疗手足口病的临床效果观察  

Clinical effect observation on the treatment of hand foot and mouth disease with the combination of the Shufeng Jiedu Capsules and Ribavirin

作　　者：张文忠[1] 

机构地区：[1]郑州市第六人民医院儿科,河南郑州450005

出　　处：《中国当代医药》2016年第31期110-112,共3页China Modern Medicine

摘　　要：目的 探讨疏风解毒胶囊联合利巴韦林治疗儿童手足口病的临床效果。方法 选择2014年12月-2015年12月我院儿科临床诊断为手足口病普通型患儿60例,采用随机数字表法随机分为两组。常规治疗组（简称对照组）采用利巴韦林注射液治疗;疏风解毒胶囊组（观察组）采用利巴韦林联合疏风解毒胶囊治疗,疗程5 d,治疗结束后随访3 d。观察两组患儿皮疹消退时间、口腔疱疹消退时间及退热时间。结果 治疗后,观察组皮疹消退时间为（2.52±0.26）d,对照组为（4.01±0.57）d,观察组明显短于对照组,差异有统计学意义（P〈0.05）;观察组疱疹消退时间为（2.31±0.31）d,对照组为（3.46±0.57）d,观察组明显短于对照组,差异有统计学意义（P〈0.05）;治疗后,观察组体温为（36.8±0.5）℃,对照组为（37.5±0.5）℃,差异有统计学意义（P〈0.05）;观察组退热时间为（2.2±1.1）d,对照组为（4.3±1.4）d,观察组明显短于对照组,差异有统计学意义（P〈0.05）。结论 疏风解毒胶囊联合利巴韦林治疗儿童手足口病具有较好的临床效果,值得临床推广。Objective To investigate the clinical effect of the treatment of children with hand foot and mouth disease by the combination of ShuFeng Jiedu Capsules and Ribavirin.Methods 60 patients from December 2014 to December 2015 in our hospital with pediatric clinical diagnosis of hand,foot and mouth disease in children with of general type were selected,according to the random number method,were randomly divided into two groups.The conventional treat- ment group （the control group） was treated with Ribavirin Injection,and the treatment group （observation group） was treated with Ribavirin combined with Shufeng Jiedu Capsules after treatment 5 days,and the patients were followed up for 3 days after the treatment.The children with rash subsided,oral herpes subsided time and cooling time of two groups were compared.Results After the treatment,the rash subsided time of observation group was （2.52±0.26） days,the control group was （4.01±0.57） days,the observation group was significantly shorter than that of control group,the difference was significant （P〈0.05）;the blebsubsidise time of observation group was （2.31±0.31） days,the control group was （3.46±0.57） days,the observation group was significantly shorter than that of control group,the difference was significant （P〈0.05）;after treatment,the observation group body temperature was （36.8±0.5）℃,the control group was （37.5±0.5）℃,the difference was significant （P〈0.05）;the cooling time of observation group was （2.2±1.1） days,the control group was （4.3±1.4） days, the observation group was significantly shorter than that of control group,the difference was significant （P〈0.05）.Con clusion Shufeng Jiedu Capsules combined with Ribavirin has better clinical efficacy in the treatment of children with hand foot and mouth disease,it is worthy of promotion.

关 键 词：手足口病 疏风解毒胶囊 利巴韦林 临床疗效 

分 类 号：R816.92[医药卫生—放射医学]