首次血清转氨酶水平预测急诊经皮冠状动脉腔内成形术的ST段抬高型心肌梗死患者的预后价值  被引量:5

Initial serum transaminase levels predict outcomes in patients with acute ST-segment elevation myocardial infarction who undergo primary percutaneous coronary intervention

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作  者:林奔腾 王海鹏[1] 赵欣[1] 程绪杰[1] 许海峰[1] 贺永明[1] 周亚峰[1] 杨向军[1] 

机构地区:[1]苏州大学附属第一医院心内科,215006

出  处:《中华老年医学杂志》2016年第11期1164-1167,共4页Chinese Journal of Geriatrics

基  金:国家自然科学基金(81170178)

摘  要:目的评估ST段抬高型心肌梗死(STEMI)患者缺氧性肝损伤(HLI)的发生率以及对预后判断的价值。方法选择从2013年1月1号至2015年8月1号的行急诊经皮冠状动脉腔内成形术(PCI)的STEMI的患者,通过回顾分析病例及电话随访患者或家属来评估。结果共有622例STEMI患者行急诊PCI,平均年龄62(18)岁,男性534例,37例STEMI患者(5.9%)在我们的随访中死亡632(495)d,这些sTEMI患者具有年龄更大70(17)岁比62(18)岁,更高的血清谷丙转氨酶值625(695)U/L比247(236)U/L、血清谷草转氨酶值123(133)u/L比52(42)u/L肌酸激酶-MB值248.5(407.5)ng/ml比184.7(197.0)ng/ml和肌钙蛋白I80.0(30.4)ng/ml vs.49.6(61.6)ng/ml,均P〈O.05。结论行急诊PCI术的STEMI患者出现缺氧性的肝损伤是常见的,并预示着更高的死亡率。Objective To evaluate the prevalence and prognostic implications of hypoxic liver injury(HLI)in acute ST-segment elevation myocardial infarction(STEMI). Methods Patients with STEMI who had undergone primary percutaneous coronary intervention (PCI)were enrolled from January 2013 to August 2015. Patients' medical records were reviewed and their families were interviewed via telephone to assess the outcomes. Results Of the 622 STEMI patients(aged 62(18) years, with 534 males), 37 patients ( 5.9%) died during the follow-up ( duration: 632 (495) days). These patients were older and had higher AST 625(695)U/L vs. 247(236)U/L,ALT 123(133)U/L,vs. 52 (42) U/L, creatine kinase-myocardial band isoenzyme 248. 5 (407. 5) ng/ml vs. 184. 7 ( 197. 0) ng/ml and troponin I 80. 0(30. 4)ng/ml vs. 49.6 (61.6)ng/ml from the initial tests at the hospital. Particularly, AST and ALT independently predicted albcause mortality. Conclusions The presence of HLI is common and predicts mortality in patients with STEMI who undergo primary PCI.

关 键 词:转氨酶类 心肌梗死  

分 类 号:R542.22[医药卫生—心血管疾病]

 

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