基于“细菌负荷阈值”理论的扶正祛邪法治疗慢阻肺的思路  

Thinking of Strengthening Healthy-Qi and Eliminating Evil Treatment in Treating COPD on the Basis of Bacterial Load Threshold

作　　者：封继宏[1,2] 李美凤[2] 祁海燕[3] 孙增涛[2] 

机构地区：[1]中国中医科学院博士后科研流动站,北京100701 [2]天津中医药大学第二附属医院 [3]天津中医药大学

出　　处：《西部中医药》2016年第9期47-51,共5页Western Journal of Traditional Chinese Medicine

基　　金：国家自然基金青年基金项目(编号81202796);全国中医药传承博士后项目(国中医药人教函[2013]240号)

摘　　要：根据传统中医理论和长期临床实践,结合现代医学细菌负荷理论提出慢性阻塞性肺疾病(COPD)稳定期的"正虚邪郁"病机理论,正虚是指肺脾肾亏虚,而以肺气虚为始,以肾虚为渐,以气虚为本,涉及阴阳;邪郁是指细菌、病毒、烟尘等毒邪乘虚侵犯肺脏,毒损肺络,肺叶不举,升降失常,痰浊水湿瘀血胶痼积蓄。同时拟通过体内外实验,而且基于"细菌负荷阈值"理论从整体和细胞水平研究扶正祛邪中药的抑菌机制,诠释其本质和内涵,为COPD稳定期的治疗提供新方法。According to TCM theory and a long period of clinical practice combined with bacterial load theory of modern medicine,the pathogenesis theory of healthy-Qi deficiency and evil stagnation of COPD at stable period was raised,healthy-Qi deficiency referred to deficiency of lung,spleen and kidney,from lung Qi deficiency to kidney deficiency,and it was related to Yin and Yang;evil stagnation referred to invasion of bacteria,virus and smoke dust into lung,causing pulmonary collaterals lesion,lung lobe impotence,disorder of going up and down and stagnation of phlegm,turbid,water-dampness,congestion.Antifungal mechanism of strengthening healthy-Qi and eliminating evil Chinese herbs from holism and cellular level was explored through experiments in vitro and vivo based on bacterial load threshold theory,its nature and content were explained,therefore to provide new treatment methods for COPD at stable stage.

关 键 词：慢性阻塞性肺疾病 细菌负荷阈值 扶正祛邪法 

分 类 号：R563[医药卫生—呼吸系统]