基于GC-MS的六经头痛片挥发性化学成分研究  

Analysis on volatile components of Liujing Toutong Tablets based on GC-MS

作　　者：张晓燕[1] 龚苏晓[2] 游飞祥 王月红[3] 韩彦琪[2] 许浚[2] 陈常青[2] 张铁军[2] 

机构地区：[1]天津中医药大学,天津300193 [2]天津药物研究院,天津300193 [3]天津医科大学,天津300070

出　　处：《中草药》2016年第21期3787-3794,共8页Chinese Traditional and Herbal Drugs

摘　　要：目的通过GC-MS法分析六经头痛片中挥发性成分。方法利用水蒸气蒸馏法提取六经头痛片挥发油,运用GC-MS联用技术对提取物进行成分分析,谱库检索结合药材色谱峰归属对六经头痛片挥发油进行定性分析,应用峰面积百分比法计算相对量。结果从六经头痛片挥发油中共鉴定出102个成分,其中薄荷酮(11.887%)相对量最高,另对各色谱峰进行药材归属,其中87个色谱峰已归属至药材,占已鉴定总峰个数的85.3%。结论通过GC-MS法能够快速有效地分析六经头痛片中的挥发性成分,为六经头痛片药效成分的研究和质量控制提供参考。Objective To analyze the components of oil from Liujing Toutong Tablets by GC-MS. Methods Steam distillation was used to extract the oil from Liujing Toutong Tablets, GC-MS was used to analyze the components, the components analyzed with the different kinds of condition; The optimum separated and analytical conditions were researched, the amount of the components from the essential oil were determined by normalization method. Results All 102 components which 87 peaks have been attributed to herbs about 85.3% of the total essential oil were separated and identified, including menthone （11.887%） is calculated as the relative content of the highest. Conclusion GC-MS is stable, reliable and reproducible. It is suitable for the quick analysis of volatile oil from Liujing Toutong Tablets.

关 键 词：六经头痛片 GC-MS 挥发油 薄荷酮 色谱峰 

分 类 号：R284.1[医药卫生—中药学]