保定市乙肝疫苗查漏补种前后15岁以下人群发病对比分析  

Comparative analysis of supplementary immunization vaccination strategy of hepatitis B vaccine before and after of population under the age of 15 in Baoding City

作　　者：马丽娜[1] 张玉玺[1] 左志平[1] 吴冰冰[1] 李淑芳[1] 曹丽霞[1] 张利[1] 

机构地区：[1]保定市疾病预防控制中心,河北071000

出　　处：《医学动物防制》2016年第11期1229-1231,共3页Journal of Medical Pest Control

摘　　要：目的对保定市乙肝疫苗查漏补种前后5年（2005-2009年与2010-2014年）15岁以下乙型病毒性肝炎的流行病学特征进行对比分析,并评价乙肝疫苗查漏补种效果及免疫策略。方法对中国免疫规划监测信息管理系统（China Immunization Program Monitoring Information Management System,CIPMIS）中（乙型肝炎病例个案调查表）报告的保定市2005-2014年15岁以下乙肝病例,分成两个阶段,采用流行病学方法对其特征进行分析。结果 2010-2014年较2005-2009年系统报告病例数减少了87.65%,发病率下降了89.45%。前后5年发病率对比差异有统计学意义（χ2=642.58,P〈0.01）;地区分布前后5年比较发病率有16个县无病例报告,除16个县外减少最多的分别是望都98.38%、唐县97.57%、高阳95.25%、易县91.18%、曲阳86.49%;从8-岁组开始,发病率随着年龄的增长呈上升趋势,2-岁组发病率减少不明显,2010-2014年较2005-2009年4-14岁组发病率明显下降,13-岁组下降了94.31%。其中13-岁组前后5年间比较差异有统计学意义（χ2=118.84,P〈0.01）。结论 15岁以下人群查漏补种工作对降低乙肝发病率起到了一定作用。随着漏种人群的积累,适时开展查漏补种工作将在一定程度上控制乙肝发病。Objetive In Baoding City before and after Supplementary immunization of hepatitis B vaccine in 5 years （from 2005 to 2009 and 2010 to 2014） comparative analysis of the epidemiological characteristics of hepatitis B under 15 years of age, and to evaluate the effect of hepatitis B vaccine supplementary immunization vaccination and immunization strategy. Methods To the China Immunization Program Monitoring Information Management System （CIPMIS） （hepatitis B case questionnaire）, the report of the Baoding city 15 years of age in the case of hepatitis B from 2005 to 2014, divided into two stages, analysis of the charac- teristics of the epidemiologieal method. Results The number of reported cases of the 2010 - 2013 system compare with the 2005 -2009 was decreased by 87. 65% , the incidence decreased by 89.45%. The 5 years before and after have incidence of statisti- cal significance （χ2 = 642.58, P 〈 0. 01 ） ; before and after the five - year regional distribution compare the incidence of 16 counties reporting no cases, in addition to the 16 counties outside the county, the largest decline in the county respectively, Wangdu County 98. 38% , Tangxian County 97. 57% , Gaoyang County 95.25%, Yixian County 91.18%, Quyang County 86. 49% ; the age of onset of age from 8- years old with the increase of age, 2 years old incidence rate decline is not obvious, the 2010-2013 compare with 2005 -2009 of 4 -14 years of age were significantly decreased, 13 - year old group fell by 94. 31%. Among them 13 years old group, 5 years before and after comparison have very significant statisticalsignificance（χ2 = 118. 84, P 〈0. 01 ）. Conclusion Supplementary immunization vaccination under the age of 15 to on reduce the incidence of hepatitis B has played a certain role. With the accumulation non - vaccinated crowd, timely conduct supplementary immunization vaccination work, to control the incidence of hepatitis B in a certain extent.

关 键 词：15岁以下 乙型肝炎 查漏补种 对比分析 

分 类 号：R186[医药卫生—流行病学]