Aberrant ketolysis fuels hepatocellular cancer progression  

作　　者：Lorenzo Galluzz Guido Kroemer 

机构地区：[1]Deparmtent of Radiation Oncology, Weill Cornell Medical College, New York, NY 10065. USA [2]Equipe ll labellisee Ligue contre le Cancer, Centre de Recherehe des Cordeliers, 75006 Paris, France [3]INSERM, U1138, 75006 Paris, France [4]Universite, Paris Descartes/Paris V. Sorbonne Paris Cite. 75006 Paris, France [5]Universite Pierre et Marie Curie/Paris Ⅵ, 75006 Paris, France [6]Gustave Roussy Comprehensive Cancer Institute, 94805 Villejuif France [7]Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, 94805 Villejuif France [8]Pole de Biologie, Hopital Europeen George Pompidou, AP-HP, 75015 Paris. France [9]Department of Women's and Children's Health, Karolinska Univeersity Hospital, 17176 Stockholm, Sweden

出　　处：《Cell Research》2016年第10期1077-1078,共2页细胞研究（英文版）

摘　　要：At odds with their normal counterparts, hepatocellular carcinoma cells efficiently utilize ketone bodies to proliferate despite serum deprivation. These findings, which have been recently published in Cell Research, identify a novel metabolic circuitry through which tumors successfully cope with adverse microenvironmental conditions.

分 类 号：Q[生物学]