糠酸莫米松鼻喷剂浸泡明胶海绵在鼻内镜术后的应用  

Application of Gelatin Sponge with Momestasone Furoate Aqueous Nasal Spray after Endoscopic Sinus Surgery

作　　者：林彬[1] 王挥戈[1] LIN Bin WANG Hui-ge(Department of Otolaryngology , The First Affiliated Hospital, Shantou University Medical College, Shantou 515041, China)

机构地区：[1]汕头大学医学院第一附属医院耳鼻咽喉科,广东汕头515041

出　　处：《汕头大学医学院学报》2016年第3期154-155,F0004,共3页Journal of Shantou University Medical College

摘　　要：目的:观察糠酸莫米松鼻喷剂浸泡明胶海绵在鼻内镜鼻窦手术后的疗效和安全性。方法:鼻内镜鼻窦术后患者(60例)随机分为实验组(30例。鼻腔局部用糠酸莫米松鼻喷剂浸泡的明胶海绵,1周后重复1次)和对照组(30例。NS冲洗鼻腔,每天2次;糠酸莫米松鼻喷剂喷鼻,每天1次,每次2喷),并同时口服克林霉素2周。2周后复查鼻内镜,对鼻黏膜形态进行评分。结果:实验组鼻腔黏膜形态评分明显高于对照组(P<0.05)。结论:糠酸莫米松鼻喷剂浸泡明胶海绵在鼻内镜鼻窦手术后鼻腔局部应用疗效可靠,不良反应发生率低。Objective： To observe the effects and safety of gelatin sponge with momestasone furoate aqueous nasal spray after endoscopic sinus surgery. Methods： Sixty patients aiter endoscopic sinus surgery were divided into experimental group （30 cases, local application of gelatin sponge with momestasone furoate, repeated once ailer one week）and control group （30 cases, washing nasal sinus by normal saline, twice a day, and spraying noses by momestasone furoate aqueous nasal spray, once two times, once a day）. Oral clindamycin was taken for two weeks at the same time. Two weeks later, the patients were examined by endoscopy and evaluated by Lund-Kennedy endoscopic mucosal morphology scoring system. Results： The mucosal morphology scoring in the experimental group was higher than that in the control group （P〈0.05）. Conclusion： Application of gelatin sponge with momestasone furoate aqueous nasal spray after endoscopic sinus surgery is reliable for curative effect and less side effects.

关 键 词：糠酸莫米松鼻喷剂 鼻内镜鼻窦手术 明胶海绵 

分 类 号：R765[医药卫生—耳鼻咽喉科]