常州市待孕夫妇乙肝五项检测结果分析  

Analysis of Five Hepatitis B Examination Results Among Pre-Pregnancy Couples in Changzhou City

作　　者：汪晓东[1,2] 张秀敏[1] 刘妍妤 董兰 吴方园[1] 刘莹圆 李眩眩 刘红箭[1] 

机构地区：[1]吉林大学公共卫生学院,长春130021 [2]常州市卫生和计划生育委员会,常州213022

出　　处：《医学与社会》2016年第11期4-7,共4页Medicine and Society

基　　金：常州市计划生育委员会项目;编号为2013(216)

摘　　要：目的:了解常州市待孕夫妇乙肝表面抗原(HBs Ag)及乙肝表面抗体(HBs Ab)阳性情况,根据检测结果为受检夫妇提供有针对性的干预策略。方法:收集2013年常州市参加孕前优生健康检查的全部10152对夫妇的一般信息和乙肝五项检测结果,进行统计分析。结果:常州市受检夫妇乙肝表面抗原(HBs Ag)阳性率男性为5.7%,女性为3.6%;大三阳模式男性为0.65%,女性为0.59%;小三阳模式男性为3.85%,女性为2.38%。单纯有抗体(HBs Ab阳性)的比例男性为41.16%,女性为40.42%。五项检测全为阴性的比例男性为47.49%,女性为47.62%。年龄、文化程度、职业、户口性质不同的受检夫妇单纯具备乙肝保护性抗体的情况差别有统计学意义(P<0.005);文化程度、职业、户口性质不同的受检夫妇五项检测均为阴性的人群分布情况差别有统计学意义(P<0.001)。结论:常州市待孕夫妇中乙肝表面抗原(HBs Ag)阳性者比例较高,具备乙肝病毒保护性抗体者的比例尚待提高,相关部门应根据受检夫妇检测结果提供有针对性的干预策略,有效预防新生儿感染乙肝病毒。Objective： To analysis the situation of hepatitis B surface antigen （HBsAg） positive and hepatitis B surface antigen （HBsAb） positive about pre-pregnancy couples in Changzhou City. According to the results, intervention strategies were provided to all couples. Methods： Collected general information and hepatitis B five test results of all 10152 couples of pre-pregnancy health check in 2013, established a database for statistical analysis. Results： Among the inspection couples, hepatitis B surface antigen （HBsAg） positive rate of male was 5.7%, female was 3.6%, HBsAg, HBeAg, and HBcAb test positive of male was 0.65%, women was 0.59% ; HBsAg, HBeAb, and HBcAb test positive of male was 3.85%, women was 2.38%. The proportion of hepatitis B surface antigen （HBsAb） positive of male was 41.16%, female was 40.42%. The pro- portion of five tests all negative of male was 47.49%, female was 47.62%. There were statistically significant differences between the tested cou- ples with different age, education, occupation, residence in the case of protective antibodies against hepatitis B virus （P〈0.001）. There were sta- tistically significant differences in the distribution of the tested couples with different education, occupation, residence who had negative hepatitis B five tests resuhs（P〈0.001）. Conclusion： The proportion of hepatitis B surface antigen （HBsAg） positive among the pre-pregnancy health check couples in Changzhou was high, and the proportion of hepatitis B virus protective antibody needed to be improved. The relevant departments should provide targeted intervention strategies according to the relevant departments at all levels to make a contribution to the prevention of hepati- tis B infection in newborn infants.

关 键 词：乙肝五项检测 待孕夫妇 常州 

分 类 号：R194.3[医药卫生—卫生事业管理]