健康风险评估系统对不同心血管健康状态人群颈动脉硬化的评估研究  

Evaluation of application of health risk appraisal for carotid atherosclerosis in cases with varied cardiovascular health

作　　者：周海跃 邓笑伟[1] 赵美玉[1] 刘侠[1] 王雅涵[1] 

机构地区：[1]北京武警总医院健康医学中心,北京100039

出　　处：《中国现代医学杂志》2016年第20期115-119,共5页China Journal of Modern Medicine

摘　　要：目的评价健康风险评估(HRA)系统对心血管系统疾病及颈动脉硬化早期诊断的应用价值,探讨颈动脉硬化与心血管健康状态的相关性。方法选取北京武警总医院健康医学中心体检的600人作为研究对象,对其进行统一问卷调查、血生化检查及颈动脉超声检查,进行心血管健康状态评估。HRA系统检测其心血管及左、右颈动脉的功能状态。结果在600例研究对象中,理想心血管健康水平的有32人,一般心血管水平的有552人,较差心血管水平的有16人。理想心血管健康水平的发生率为5.3%。理想组中仍有9例存在心血管功能异常,一般组中有467例存在心血管功能异常,较差组有15例存在心血管功能异常,且差异有统计学意义(χ2=68.0,P<0.01)。HRA系统对颈动脉的敏感度为83.8%。理想组中有颈动脉斑块的4人,有内中膜(IMT)增厚的5人。一般组中有颈动脉斑块的152人,有IMT增厚的180人。差组中有颈动脉斑块的7人,有IMT增厚的9人。结论 HRA系统能早期评估心血管及颈动脉的功能变化,可作为心血管系统疾病及颈动脉硬化早期筛查的工具。心血管健康状态理想条目数越多,颈动脉IMT增厚和斑块的发生率越低。Objective To evaluate the application of Health Risk Appraisal （HRA） in the early diagnosis of cardiovascular disease and carotid atherosclerosis, and to explore the relationship between carotid atherosclerosis and cardiovascular health. Methods We included 600 people who came to our center for physical examination. We used questionnaire, blood and biomedical tests and carotid uhrasonography to evaluate the cardiovascular health of the subjects, and HRA to evaluate the function of cardiovascular and left ＆ right carotid artery. Results Six hundred cases were included, and 32 cases had ideal cardiovascular health, 552 cases bad normal cardiovascular health, and 16 cases had sub-normal cardiovascular health. The proportion of subjects with ideal cardiovascular health was 5.3%. There were 9 cases, 467 cases and 15 cases with cardiovascular dysfunction among the ideal group, the normal group and the sub-normal group respectively. The differences were significant （χ^2= 68.0,P 〈 0.01 ）. The sensitivity of HRA for carotid function was 83.8%. In the ideal group, there were 4 cases with carotid plaque and 5 cases with carotid intima-media thickness （IMT）. In the normal group, there were 152 cases with carotid plaque and 180 cases with IMT. In the sub-normal group, there were 7 cases with carotid plaque and 9 cases with IMT. Conclusions HRA can evaluate early functional changes of cardiovascular and carotid artery. It can be used for early screening for cardiovascular diseases and carotid plaque.

关 键 词：健康风险评估系统 心血管健康状态 颈动脉硬化 

分 类 号：R194.3[医药卫生—卫生事业管理]