重庆市7～16岁儿童青少年代谢综合征组分的调查及影响因素的分析  

Survey on components of the metabolic syndrome and analysis of its influencing factors among 7-16 years old children and adolescents in Chongqing

作　　者：王嫣嫣[1] 熊丰[1] 张亚妮 杨彬 林琴[1] 朱岷[1] 曾燕[1] 罗雁红[1] 宋萃[1] 朱高慧[1] Wang Yanyan Xiong Feng Zhang Yani Yang Bin Lin Qin Zhu Min Zeng Yan Luo Yanhong Song Cui Zhu Gaohui(Department of Endocrinology, the Children＇s Hospital,Chongqing Medical University Primary and Secondary School Health Institute of Shapingba District of Chongqing)

机构地区：[1]重庆医科大学附属儿童医院内分泌科,重庆400014 [2]重庆市沙坪坝区中小学生卫生保健所,重庆400030

出　　处：《重庆医科大学学报》2016年第10期1069-1075,共7页Journal of Chongqing Medical University

基　　金：国家科技支撑计划资助项目(编号:2009BAI80B00)

摘　　要：目的：探讨重庆市7~16岁儿童青少年代谢综合征（metabolic syndrome,MS）的组分及其影响因素,为有针对性的干预提供流行病学依据。方法：按照整群随机抽样方法抽取重庆市5所中小学7~16岁在校生共4481名进行代谢指标及影响因素问卷调查。按照体质指数（body mass index,BMI）法分为正常组、超重组、肥胖组。对各代谢指标进行分析,对MS影响因素进行Logistic回归分析,并比较MS影响因素的性别差异。结果：（1）重庆地区7~16岁儿童青少年总超重率9.8%,其中男生12.0%,女生7.4%。总肥胖率5.4%,其中男生7.3%,女生3.4%。男生超重率、肥胖率均高于女生（P〈0.05）。（2）随着BMI的增加,收缩压、舒张压、甘油三酯、胆固醇、低密度脂蛋白胆固醇、非高密度脂蛋白胆固醇、腰围有升高的趋势,高密度脂蛋白胆固醇呈降低趋势（P〈0.05）。（3）MS总体检出率为0.45%。肥胖组MS的患病率（6.9%）明显高于超重组（0.5%）和正常组（0.0%）（P〈0.05）,且男生患病率高于女生（P〈0.05）。肥胖儿童MS出现单项异常的检出率依次为高腰围（37.9%）、高甘油三酯（22.7%）、低高密度脂蛋白（19.7%）、高非高密度脂蛋白（7.4%）、高血压（4.4%）、高空腹血浆葡萄糖（2.0%）。（4）MS影响因素logistic回归分析结果显示,有3个因素与MS相关：腰围、每次肉类摄入量、高血脂家族史均与MS的发病率呈正相关。男生高腰围、每次肉类摄入量≥3两检出率高于女生（P〈0.05）。结论：MS组分异常已在重庆地区超重肥胖儿童青少年中发生。高腰围、高甘油三酯、低高密度脂蛋白是重庆肥胖儿童最常见的代谢异常,应引起社会的重视。Objective：To study the components of the metabolic syndrome and its influencing factors among 7-16 years old children and adolescents in Chongqing,in order to provide the evidence for a target precaution. Methods：According to the method of cluster random sampling,4 481 school-age children aged 7 to 16 years old were enrolled from 5 middle schools and primary schools（2 urban schools and 3 rural schools）of Chongqing to measure metabolic index and to fill influencing factors questionnaires. Children were divided into normal group,overweight group and obese group according to body mass index（BMI）. The metabolic indices,influencing factors of metabolic syndrome were analyzed by logistic regression analysis,and the differences between boys and girls were compared. Results：（1）Overall overweight incidences among 7-16 years old children and adolescents in Chongqing were 9.8%,12.0% in boys and 7.4% in girls. Overall obesity incidences were 5.4%,7.3% in boys and 3.4% in girls（P〈0.05）.（2）With increased BMI,the levels of systolic blood pressure,diastolic blood pressure,triglycerides（TG）,cholesterol,low-density lipoprotein cholesterol（LDL-C）,non-high-density lipoprotein cholesterol（nonHDL-C）,waist circumference（WC） were also increased,the level of high- density lipoprotein- cholesterol（HDL- C） was reduced（P〈0.05）.（3）The overall prevalence of metabolic syndrome was 0.45%. In obese group,children had significantly higher MS prevalence（6.9%）compared with their counterparts in overweight group（0.5%）and normal weight group（0.0%）（P〈0.05）;the prevalence of MS in boys was higher than that in girls（P〈0.05）.The detective rates of individual MS component among obese children were：37.9% for high WC,22.7% for high TG,19.7% for low HDL-C,7.4% for high non-HDL-C,4.4% for elevated blood pressure,2.0% for fasting plasma glucose.（4）MS logistic regression analysis demonstrated that WC,meat intake,and family history of hyperlipidemia were risk factors. Boys ha

关 键 词：儿童青少年 肥胖 代谢综合征 组分 影响因素 

分 类 号：R725.8[医药卫生—儿科]