2011-2015年不同年龄段男女患者泌尿生殖道支原体感染状况及耐药性调查  

Incidence of infection and drug resistance of mycoplasma among patients with urinary tract infection in different age groups from 2011 to 2015

作　　者：黄荣富[1] 姚建凤[2] 黄宝陕 黄东红[3] HUANG Rongfu YAO Jianfeng HUANG Baoshan HUANG Donghong(Laboratory Department, Donghai Branch of Fujian Medical University Second Affiliated Hospital, Quanzhou, Fujian 362000, Chin)

机构地区：[1]福建医科大学附属第二医院东海院区检验科,福建泉州362000 [2]泉州市儿童医院生殖医学中心,福建泉州362000 [3]福建医科大学附属第二医院检验科,福建泉州362000

出　　处：《中国微生态学杂志》2016年第11期1316-1319,共4页Chinese Journal of Microecology

摘　　要：目的了解本地区男女患者泌尿生殖道支原体感染状况及耐药特征,为临床诊疗及合理用药提供依据。方法选取2011年1月-2015年12月门诊及住院患者,采集泌尿生殖道标本做支原体培养,并对阳性标本进行药敏试验,对阳性标本及其药敏结果进行分析。结果 2011-2015年男女患者的感染率和总感染率呈逐年递增趋势（P〈0.01）,女性感染者高于男性,男女患者均以Uu单纯感染为主,不同年度均以21~30岁年龄段患者为主,占合计的51.0%,药敏试验表明Uu＋Mh混合感染的耐药率明显高于Uu、Mh单纯感染,Uu＋Mh混合感染对克拉霉素、阿奇霉素、罗红霉素、环丙沙星的耐药率均〉90.0%,Uu、Mh和Uu＋Mh对美满霉素、强力霉素、交沙霉素的耐药率较低,均〈10.0%。结论本地区支原体感染呈逐年上升趋势,女性感染率高于男性,年龄21~30岁患者居多,并以Uu单纯感染为主,治疗支原体感染首选美满霉素、强力霉素、交沙霉素。Objective To understand the incidence of infection and drug resistance of mycoplasma among male and female patients with urinary tract infection and provide the basis for clinical diagnosis,treatment and rational use of drugs.Methods Outpatients and inpatients from January 2011 to December 2015 were selected;specimens were collected from urogenital tract to cultivate mycoplasma.The positive specimens and results of drug sensitivity test were analyzed.Results The infection rate and total infection rate had been increasing year by year（P〈0.01）,with the rates in women higher than in men.Uu infection was predominant in both male and female patients.Patients at age of 21 to 30years accounted for 51.0%.The resistance rate of Uu-Mh mixed infection was significantly higher than that of Uu or Mh infection.The resistance rates of Uu-Mh infection to clarithromycin,roxithromycin,azithromycin and ciprofloxacin were higher than90.0%,while those of Uu,Mh and Uu-Mh infections to minocycline,doxycycline and josamycin were lower than 10.0%.Conclusion The incidence of mycoplasma infections in the local area was increasing year by year,with the infection rate in women higher than in men.Most of the patients were at age of 21 to 30years,and Uu infection was predominant.Minocycline,doxycycline and josamycin can be the drugs of choice to treat mycoplasma infections.

关 键 词：泌尿生殖道 支原体 感染 耐药性 

分 类 号：R378[医药卫生—病原生物学]