氧化微纤化纤维素/海藻酸钠/胶原复合水凝胶的研究  

Study on composite hydrogels of oxidized microfibrillated cellulose,sodium alginate and collagen

作　　者：田伟[1] 王芳[1] 汤克勇[1] 余鑫[1] TIAN Wei WANG Fang TANG Keyong YU Xin(College of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China)

机构地区：[1]郑州大学材料科学与工程学院,河南郑州450001

出　　处：《中国皮革》2016年第11期20-22,28,共4页China Leather

基　　金：国家自然科学基金(51373158);河南省科技创新杰出人才(No.144200510018)

摘　　要：以胶原、海藻酸钠和氧化微纤化纤维素为原料制备了氧化微纤化纤维素/海藻酸钠/胶原(OMFC/SA/Col)复合水凝胶。用红外光谱、扫描电镜分析了复合水凝胶的结构和形貌,通过接触角和压缩试验研究了其亲水性和力学性能。结果表明:OMFC和胶原间发生了席夫碱反应;复合水凝胶在20%应变时的压缩应力可达0.45MPa,可满足软骨浅表层的要求;其应变可达90%以上,韧性好;其亲水性好,OMFC含量对其亲水性影响不大。Oxidized microcrystalline cellulose/sodium alginate/ collagen （OMFC/SA/Col） composite hydrogels were pre- pared by using Col of pig skins, SA and OMFC as main raw materials. The structure and morphology of the composite hydrogels were analyzed by infrared spectroscopy （FT- IR） and scanning electron microscope （SEM）. The hydrophilicity and mechanical properties of the composite were studied by contact angle test and compression test. The results of FT - IR and SEM indicate that Schiff base reaction has happened between OMFC and Col. The maximum compression stress could reach 0. 45 MPa at the deform- ation of 20%, meeting the needs of superficial cartilage. The deformation can reach 90%. Both toughness and hydrophilicity of the composite hydrogels are good. There is no significant difference on hydrophilic properties of the composite hydrogel between different contents of OMFC.

关 键 词：微纤化纤维素 海藻酸钠 胶原 水凝胶 亲水性 力学性能 

分 类 号：TQ427.26[化学工程]