脾动脉主干截流术与脾动脉部分栓塞术治疗脾功能亢进疗效对比观察  

Splenic artery trunk embolization technique versus splenic artery partial embolization for treatment of hypersplenism

作　　者：覃祖云 程昌盛 

机构地区：[1]广西桂东人民医院肝科,广西梧州543001

出　　处：《右江民族医学院学报》2016年第5期498-500,共3页Journal of Youjiang Medical University for Nationalities

摘　　要：目的为脾功能亢进患者选择更适合的微创手术。方法选择在我科住院的脾肿大脾功能亢进病人128例为研究对象,根据入院时间单双日分为两组,A组62例行脾动脉主干截流术,B组66例行脾动脉部分栓塞术。观察术后1个月白细胞、血小板、红细胞变化情况,不良反应发生的例数。结果两组术后白细胞计数和血小板计数明显升高,两组对比结果显示白细胞计数(t=0.34)、血小板计数(t=0.47),差异无统计学意义(P>0.05);两组不良反应发生率对比,其中剧痛(χ2=78.12)、高烧(χ2=41.55)、腹水(χ2=56.92),对比差异有统计学意义(P<0.001),B组明显高于A组。结论脾动脉截流术与脾动脉部分栓塞术治疗脾功能亢进的疗效相同,脾动脉部分栓塞术不良反应大,治疗肝硬化脾功能亢进建议选用脾动脉主干截流术。Objective To choose suitable minimally invasive surgery for patients with hypersplenism. Methods A total of 128 patients with splenomegaly hypersplenism hospitalized at our department were chosen as the research objects,according to admission time of single or double day,patients were divided into two groups,62 cases of group A underwent splenic artery trunk embolization,66 cases of group B underwent par-tial splenic artery embolization.One month after operation,the changes of white blood cells,platelets,red blood cells and the number of adverse reaction were observed. Results In both groups,the postoperative white blood cells and platelet count were elevated,comparison of group A with group B showed white blood cell counts （t = 0.34）,platelet count （t = 0.47 ）,there were no statistically significant differences （P〉0.05）.Comparison of adverse reaction incidence between the two groups was performed,of which sharp pain （χ2 =78.12）,high fever （χ2 =41.55）,ascites （χ2 =56.92）,there were statistically significant differences （P〈0.001）,the incidence rates of group B were obviously higher than those of group A. Conclusion The cura-tive effects of splenic artery trunk embolization were the same with partial splenic artery embolization.Partial splenic artery embolization has more adverse reactions.The recommended treatment method for hypersplenism of cirrhosis is partial splenic artery embolization.

关 键 词：脾动脉截流术 脾动脉部分栓塞术 脾功能亢进 

分 类 号：R551.1[医药卫生—血液循环系统疾病]