冠状动脉微循环及评估方法简介  

Assessment of coronary microcirculation and function

作　　者：曹轲[1] 郭丽君[1] Cao Ke Guo Lijun(Department of Cardiology’Peking University Third Hospital,Beijing 100191 ,China)

机构地区：[1]北京大学第三医院心血管内科,北京100191

出　　处：《中国心血管杂志》2016年第5期401-404,共4页Chinese Journal of Cardiovascular Medicine

摘　　要：过去20年,研究者发现冠状动脉微循环功能障碍也是引起心肌缺血的原因之一,并且对于冠心病患者的远期预后存在影响。尽管无法直接通过影像学观察到冠状动脉微血管,但最新的有创及无创技术,可通过特定参数来反映冠状动脉微循环功能。这些技术包括通过导管检查获得的有创冠状动脉血流动力学参数,及无创的影像学检查,如磁共振、核素显像。尽管每项检查都有各自的优势及局限性,但通过这些检查让人们对冠状动脉微循环及整个冠状动脉体系的生理、病生理状态及调节有了更加深入的理解,并用于指导临床治疗。In the past 20 years,dysfunction of the coronary microcirculation was recognized as one of the causes of myocardial ischemia and associated with long-term prognosis.Although coronary microvasculature cannot be directly imaged,a number of invasive and noninvasive techniques can be used as special parameters to assess coronary microcirculation function.These techniques include invasive coronary hemodynamic parameters via coronary catheter,and noninvasive imaging such as cardiac magnetic resonance and radionuclide imaging.Each method has relative advantages and limitations, however, these techniques have provided novel insights into the physiological and pathophysiological status,the regulation of the whole coronary artery system,and guide clinical therapy to the coronary artery disease.

关 键 词：冠状动脉微循环 冠状动脉疾病 功能评估 

分 类 号：R543.3[医药卫生—心血管疾病]