蒲地蓝消炎口服液联合碘伏治疗假丝酵母菌性包皮龟头炎临床观察  

Clinical Application of Pudilan Xiaoyan Oral Liquid combined with Iodophor External Preparation in the Treatment of Candidal Balanoposthitis

作　　者：张虎生[1] 

机构地区：[1]江苏省兴化市中医院皮肤科,225700

出　　处：《国际生殖健康／计划生育杂志》2016年第6期480-482,共3页Journal of International Reproductive Health/Family Planning

摘　　要：目的:观察蒲地蓝消炎口服液联合碘伏外用,治疗假丝酵母菌性包皮龟头炎的疗效。方法:将120例假丝酵母菌性包皮龟头炎患者随机分为研究组及对照组,研究组(蒲地蓝消炎口服液口服联合碘伏外用)60例,对照组(2%咪康唑乳膏外用)60例。详细记录2组患者的瘙痒、红斑、丘疹、浸渍、糜烂、水疱的消退时间并进行比较。结果:治疗随访10 d时,研究组总有效率为96.67%,对照组为86.67%,2组比较差异有统计学意义(P<0.05)。研究组瘙痒、红斑、丘疹、浸渍、糜烂、水疱的消退时间分别为(1.35±0.16)d、(1.43±0.38)d、(5.72±0.66)d、(2.43±0.39)d、(4.62±0.65)d和(3.32±0.36)d,对照组则分别为(2.32±0.56)d、(2.63±0.60)d、(8.31±1.32)d、(3.93±0.81)d、(7.63±1.27)d和(4.62±0.55)d,2组比较差异有统计学意义(t值分别为12.900 9,13.087 9,13.5940,12.924 3,16.342 5和15.318 9,均P<0.001)。结论:蒲地蓝消炎口服液口服联合碘伏外用治疗假丝酵母菌性包皮龟头炎,可明显控制局部炎症反应,瘙痒、红斑、丘疹的消退时间快,可有效缩短病程,值得临床推广。Objective： To observe therapeutic efficacy of the oral Pudilan Xiaoyan oral liquid combinedwith topical iodophor external preparation in the treatment of candidal balanoposthitis. Methods ： 120 cases of candidal balanoposthitis were randomly divided into the treatment group and the control group. 60 cases in the treatment group were given the Pudilan Xiaoyan oral liquid combined with the topical iodophor preparation,and 60 cases in the control group were given the topical use of 2% miconazole cream. The regression times of pruritus, erythema, papule blisters, maceration and erosion after treatment in two groups were recorded. Results ： After 10 daysr following-up, the total effective rate of the treatment group was 96.67% and that of the control group 86.67%. There was statistical significance in the total effective rates （P〈0.05）. The regression times of pruritus,erythema, papule, blisters, maceration and erosion in the treatment group （1.35 ±0.16days, 1.43 ±0.38days, 5.72±0.66days, 2.43 ±0.39days, 4.62 ±0.65days and 3.32 ±0.36days） were significantly decreased than those in the control group （2.32±0.56days, 2.63±0.60days, 8.31±1.32days, 3.93±0.81days, 7.63±1.27days and 4.62±0.55days, t values were 12.900 9, 13.087 9, 13.594 0, 12.924 3, 16.342 5 and 15.318 9, P〈0.001）. Conclusions：The Pudilan Xiaoyanoral liquid combined with the topical use of iodophor external preparation can be recommended in the treatment of candidal balanoposthitis, with the advantages of the inhibited local inflammation and the decreased regression times of pruritus, erythema, papule, blisters, maceration and erosion, and the shorten disease course.

关 键 词：蒲地蓝消炎口服液 消炎剂(中药) 碘附 阴茎头炎 念珠菌病 咪康唑 软膏 

分 类 号：R697.2[医药卫生—泌尿科学]