辅助性T淋巴细胞22及其特征性细胞因子白细胞介素-22的研究进展  

Research progress of Helper T lymphocytes 22 cells and their characteristic cytokine interleukin-22

作　　者：张沛枫[1] 邹美银[1] 汪美华[1] 章幼奕[1] 

机构地区：[1]南通大学附属南通第三医院感染病科,南通市226006

出　　处：《中华实验和临床感染病杂志（电子版）》2016年第3期257-260,共4页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

基　　金：江苏省南通市社会发展计划项目(No.Hs2014081)

摘　　要：辅助性T淋巴细胞(Th)22是新近发现的Th细胞谱系,细胞表型为CCR4^+、CCR6^+和CCR10^+,主要通过白细胞介素-22(IL-22)发挥作用,在介导炎症反应、组织修复、创口愈合、感染性疾病、肿瘤、肝脏疾病以及自身免疫性疾病中发挥着重要作用,逐渐成为目前研究的热点;本文就其研究进展进行综述。Helper T lymphocytes（Th） 22 were the newly discovered Th cell lineage with cell phenotypes such as CCR4^＋, CCR6^＋ and CCR10^＋, which could play important roles in mediating inflammatory responses, tissue repair, wound healing, infectious diseases, tumors, liver diseases and autoimmune diseases through interleukin-22（IL-22）, and had gradually become a research hotspot. This paper reviewed about the research progress of Th22 and IL-22.

关 键 词：辅助性T淋巴细胞22 白细胞介素-22 研究进展 

分 类 号：R392.12[医药卫生—免疫学]