某院2014年上报全国细菌耐药监测网数据分析  

Analysis of the data of a hospital in 2014 reported to China Antimicroblal Resistance Survellance System

作　　者：韩利蓉 宋江勤 欧阳娟[1] 姚文丽[1] 张霞[1] 胡晓蓉[1] 

机构地区：[1]天门市第一人民医院检验科,天门市431700

出　　处：《中华实验和临床感染病杂志（电子版）》2016年第4期407-412,共6页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

摘　　要：目的通过分析本院2014年度上报全国细菌耐药监测网的数据,了解本院临床分离菌株的分布、标本来源、多重耐药菌的分布和病原菌的耐药性。方法应用WHONET 5.6软件对2014年1月至2014年12月本院临床分离的病原菌的分布、标本来源、多重耐药菌分布和药物敏感性试验进行回顾性分析。结果 4 779株病原菌中革兰阴性菌占79.92%(3 819/4 779),革兰阳性菌占20.08%(960/4 779)。排前5位的细菌分别是大肠埃希菌(1 477株,占30.91%)、肺炎克雷伯菌(677株,占14.17%)、铜绿假单胞菌(430株,9%)、不动杆菌属(290株,占6.07%)和粪肠球菌(270株,占5.65%)。临床各科室分离菌株数量排前5位的分别是儿科(801株,占16.76%)、普通外科(447株,占9.35%)、泌尿外科(424株,占8.87%)、呼吸内科(341株,占7.14%)和重症医学科(335株,占7.01%)。标本类型排列前5位的分别是呼吸道标本(1 824株,占38.17%)、尿液(1 050株,占21.97%)、分泌物(523株,占10.94%)、引流液(513株,占10.73%)和血液(361株,占7.55%)。共分离出耐甲氧西林凝固酶阴性葡萄球菌53株(53/148,35.81%),产超广谱β-内酰胺酶细菌788株(788/2221,占35.48%),耐碳青霉烯类的鲍曼不动杆菌9株(9/52,占17.31%),耐甲氧西林金黄色葡萄球菌29株(29/205,占14.15%),耐碳青霉烯类的肠杆菌科细菌15株(15/2712,占0.55%);未分离到耐青霉素肺炎链球菌和耐万古霉素肠球菌。结论通过分析2014年度耐药监测数据,了解本院临床分离菌株的分布、标本来源、多重耐药菌和细菌的耐药性,能够指导临床合理使用抗菌药物,提高临床用药的安全性。Objective To analyze the annual reporting to China Antimicroblal Resistance Survellance System data of our hospital in 2014, and to understand the distribution of hospital clinical isolates, specimen source, the distribution of drug resistance and multi-drug resistant pathogens. Methods Clinical isolates of pathogens distribution, specimen source, the distribution of multi-drug resistant and drug sensitivity test from software for January 2014 to December 2014 in our hospital were analyzed by WHONET 5.6 software, retrospectively. ResultsAmong all the 4 779 isolated, Gram-negative bacteria accounted for 79.92%（3 819/4 779）, and Gram-positive bacteria accounted for 20.08%（960/4 779）. The top five bacteria were Escherichia coli（1 477 strains, accounting for 30.91%）, Klebsiella pneumoniae（677 strains, accounting for 14.17%）, Pseudomonas aeruginosa（430 strains, accounting for 9%）, Acinetobacter（290 strains, accounting for 6.07%） and Enterococcus faecalis（270 strains, accounting for 5.65%）. The top five clinical isolates of the department were pediatric（801 strains, accounting for 16.76%）, general surgery（447 strains, accounting for 9.35%）, urology（424 strains, accounting for 8.87%）, respiratory medicine（341 strains, accounting for 7.14%） and critical care medicine（335 strains, accounting for 7.01%）. The top five types specimens were respiratory specimens（1 824 strains, accounting for 38.17%）, urine（1 050 strains, accounting for 21.97%）, secretions（523 strains, accounting for 10.94%）, drainage（513 strains, accounting for 10.73%） and blood（361 strains, accounting for 7.55%）. Methicillin-resistant coagulasenegative Staphylococci（53/148, 35.81%）, producing extended spectrum β-lactamases（788/2 221, 35.48%）, resistance to carbapenems Bowman Acinetobacter（9/52, 17.31%）, methicillin-resistant Staphylococcus aureus（29/205, 14.15%）, Enterobacteriaceae resistant to carbapenem 15（15/2 712, 0.55%） were isolated, while penicillin-resistant Stre

关 键 词：全国细菌耐药监测网 病原菌分布 耐药性 多重耐药菌 

分 类 号：R446.5[医药卫生—诊断学]