恶性梗阻性黄疸的介入治疗进展  

Advances in interventional therapy of malignant obstructive jaundice

作　　者：马少军[1] 翟仁友[1] 赵峰[1] 

机构地区：[1]天津市南开医院介入血管科,300100

出　　处：《中华介入放射学电子杂志》2016年第2期119-123,共5页Chinese Journal of Interventional Radiology：electronic edition

摘　　要：恶性梗阻性黄疸(MOJ)是临床常见病症,梗阻以肿瘤压迫胆道狭窄为主要原因,早期缺乏典型症状,手术切除率低,预后极差。经皮肝穿刺胆管引流术(PTCD)及胆道支架置入术是MOJ最有效的解决方法,能有效缓解临床症状,改善肝功能,提高患者生活质量。介入联合化疗、^(125)Ⅰ粒子植入、射频消融等方法治疗原发肿瘤,可显著延长患者生存期。术后积极抗感染治疗,可显著降低并发症。随着新一代抗肿瘤药物问世、介入器材和技术的不断进步、药膜内支架的开发与研究,为介入治疗提供了各种新的途径和手段,胆道内支架置入后有望保持长期畅通,大大延长患者生存期。Malignant obstructive jaundice （MOJ） is a common clinical disease, obstruction of the tumor to oppression biliary stricture as the main reason for the early lack of typical symptoms, surgical resection rate is low, the prognosis is poor. Through the review of domestic and foreign research in recent 5 years, we found that percutaneous transhepatic biliary drainage （PTCD） and biliary stenting are the most effective methods for malignant obstructive jaundice. This method can effectively relieve clinical symptoms, improve liver function, improve the quality of life of patients. PTCD combined with chemotherapy, 125Ⅰ seed implantation, radiofrequency ablation and other methods for primary tumor treatment, can significantly prolong survival. Postoperative active anti-infective therapy, significantly reduced complications. With the advent of a new generation of anti-tumor drugs, interventional equipment and technology advances, the development of film stents and research for interventional therapy provides a variety of new ways and means, after biliary stenting is expected to maintain long- Greatly extending the survival of patients.

关 键 词：恶性梗阻性黄疸 经皮肝穿刺胆管引流术 介入治疗 综述 

分 类 号：R730.5[医药卫生—肿瘤]