奶牛乳房炎病原菌抗生素耐药性研究进展  

Progress in the Antibiotic Resistance to the Main Pathogenic Bacteria in Dairy Cow Mastitis

作　　者：张亚茹[1] 李新圃[1] 杨峰[1] 罗金印[1] 王旭荣[1] 张哲[1] 刘龙海[1] 王丹[1] 李宏胜[1] 

机构地区：[1]中国农业科学院兰州畜牧与兽药研究所,农业部兽用药物创制重点实验室,甘肃省新兽药工程重点实验室,兰州730050

出　　处：《中国草食动物科学》2016年第6期40-44,共5页China Herbivore Science

基　　金：“十二五”国家科技支撑计划(2012BAD12B03);甘肃省科技支撑计划(144NKCA240);甘肃省农业科技创新项目(GNCX-2013-59);中国农业科学院奶牛疾病研究创新工程项目(CAAS-ASTIP-2014-LIHPS-03)

摘　　要：奶牛乳房炎是影响世界奶牛养殖业发展的最重要疾病之一,病原菌感染,尤其是葡萄球菌、链球菌和肠道菌感染是其最主要的病因。目前,抗生素治疗奶牛乳房炎仍然是最常用及最有效的方法,然而,由于抗生素不合理及大量滥用,导致奶牛乳房炎病原菌产生耐药性,且耐药菌株呈不断增多趋势,甚至出现超级耐药菌株,为奶牛乳房炎的临床治疗带来了很大的挑战。因此,文章从奶牛乳房炎主要致病菌耐药现状、耐药变化规律、产生耐药性的原因及如何减少耐药性等方面进行了综述,以期为规范临床使用抗生素和进一步提高奶牛乳房炎治疗效果提供帮助。The dairy cow mastitis is one of the most costly disease affecting the development of the world dairy agriculture,the main cause is pathogen infection,particularly staphylococcus,streptococcus and intestinal bacteria infection. At present,the antibiotic treatment is still the most commonly used and the most effective method to the dairy cow mastitis. However,due to the unreasonable and a lot of abuse antibiotic,causing cow mastitis pathogen resistance,and resistant strains showed a trend of increasing,even appear super resistant strain. It has brought great challenges for the clinical treatment of dairy cow mastitis. This article summarized from the status of main pathogenic bacteria drug resistance of dairy cow mastitis and the change rule of the drug resistance,the causes of drug resistance and how to reduce resistance for standardizing the clinical use of antibiotics and further improveing the effect of dairy cow mastitis treatment.

关 键 词：奶牛 乳房炎 病原菌 抗生素耐药性 

分 类 号：S858.23[农业科学—临床兽医学]