针刺阳陵泉、胆囊穴治疗急性胆囊炎胆绞痛的临床疗效观察  

Clinical analgesic effect of acupuncture at GB34(Yanglingquan) and EX-LE6(dannang) for biliary colic caused by acute cholecystitis

作　　者：蒋海锋[1] 赵聪[1] 汤雪峰[1] 孔宪诚[1] 沙粒[1] 阎良[1] 刘令圭 饶文龙 黄建平[1] 

机构地区：[1]上海中医药大学附属曙光医院普外科,上海200021

出　　处：《肝胆胰外科杂志》2016年第6期481-483,488,共4页Journal of Hepatopancreatobiliary Surgery

基　　金：上海市卫生和计划生育委员会中医药科研基金课题(2014LP097A)

摘　　要：目的观察针刺阳陵泉、胆囊穴对急性胆囊炎胆绞痛的临床镇痛疗效。方法收集2015年1月至2016年1月就诊于我院普外科的急性胆囊炎胆绞痛患者共60例,随机平均分成针刺组及药物组。在治疗前后对患者进行疼痛评分,并检测患者外周血浆C反应蛋白(C-Reactive Protein)、β-内啡肽(β-Endorphin,β-EP)、胆囊收缩素(Cholecystokinin,CCK)水平。结果两组患者的术前临床资料无统计学差异(P>0.05),治疗后5、10及15 min这三个时间点,针刺组的疼痛治疗有效率明显优于药物组(P<0.05),而在治疗后20、25及30 min,两组的疼痛治疗有效率无统计学差异(P>0.05)。针刺组在降低血浆CRP方面优于药物组,有统计学差异(P=0.004),但血浆β-EP及CCK的变化无统计学差异(P>0.05)。结论此次研究证实针刺对于急性胆囊炎胆绞痛治疗效果优于麻醉镇痛药联合抗胆碱能药物的镇痛效果,具有起效快、效果好、持续久的优势,同时能降低胆绞痛患者的CRP水平,安全可靠。Objective To observe the clinical analgesic effect of acupuncture at GB34 （Yanglingquan） and EX-LE6 （Dannang） for biliary colic caused by acute cholecystitis. Methods A total of 60 cases of biliary colic caused by acute cholecystitis were collected in our hospital from Jan. 2015 to Jan. 2016. Patients were randomly divided into acupuncture group and control group. From the beginning of the treatment to 30 min after the treat-ment, we collected the pain scores according to the method of Visual Analogue Scale （VAS） every 5 min, and detected C-Reactive Protein （CRP）, p-Endorphin （p-EP） and Cholecystokinin （CCK） respectively in peripheral blood before the treatment and at 5, 10, 15, 20, 25, 30 min after the treatment Results Before treatment, there was no significant statistical difference between two groups （P〉0.05）. The effective rate of pain relief in the acupuncture group was obviously superior to control group at 5, 10 and 15 min （P〈0.05） after the treatment. However, at 20, 25 and 30 min after the treatment, there were no statistical efficiency difference between the two groups （P〉0.05）. The plasma CRP after the treatment was reduced more in acupuncture group than that in con-trol group （P=0.004）, while the reduction of plasma p-EP and CCK had no statistical significance between two groups （P〉0.05）. Conclusion The effect of acupuncture treatment for biliary colic caused by acute cholecystitis is better than the narcotic analgesics combined with anticholinergic drug. Acupuncture treatment not only has the advantages of quick effect, good effect and long lasting, but also can reduce the plasma CRP of patients with biliary colic. It＇s safe and reliable.

关 键 词：针刺 胆囊穴 阳陵泉 胆绞痛 急性胆囊炎 

分 类 号：R246.1[医药卫生—针灸推拿学]