军事飞行员冠状动脉粥样硬化患者血清RBP4水平分析  

Analysis about serum rentinol binding protein 4 in the population of military pilots

作　　者：殷雪娇[1] 陈诗婷[2] 牟宗阳 罗惠兰[1] 

机构地区：[1]空军总医院干部病房,北京100142 [2]安徽医科大学空军临床学院,合肥230032 [3]贵州医科大学,贵阳550004

出　　处：《空军医学杂志》2016年第5期299-300,303,共3页Medical Journal of Air Force

基　　金：全军后勤科研"十二五"重点项目(BWS11J054)

摘　　要：目的分析军事飞行员冠状动脉粥样硬化(atherosclerosis,AS)患者血清视黄醇结合蛋白4(rentinol binding protein4,RBP4)水平变化,探讨RBP4与军事飞行员冠状动脉粥样硬化发病风险相关性。方法收集军事飞行员冠状动脉粥样硬化50例作为AS组,健康军事飞行员200名作为健康组,收集健康地勤人员200例作为对照组,通过酶联免疫吸附法测定各组血清RBP4。结果对照组、健康组及飞行员AS组血清RBP4平均水平依次升高,差异有统计学意义(P<0.05)。结论血清RBP4可以作为提示军事飞行员冠状动脉粥样硬化发病风险的指标之一,值得进一步深入研究。Objective To analyze the change of serum rentinol binding protein 4 （RBP4） in military pilots and tostudy the relationships between RBP4 and coronary atherosclerosis （AS） among military pilot. Methods Fiftey military pilots with AS （AS group）, 200 healthy military pilots （healthy group） and 200 ground crew members （control group） were enrolled. The serum RBP4 levels were measured by enzyme linked immune sorbent assay. Results The serum RBP4 levels in the AS group of military pilots were significantly higher than those of the other two groups and the serum RBP4 levels in the group of healthy military pilots were significantly higher than those of the control group （P〈0.05）. Conclusion RBP4 can be regarded as an indicator of risk of coronary atherosclerosis in military pilots. Further research is required.

关 键 词：视黄醇结合蛋白4 飞行员 冠状动脉粥样硬化 

分 类 号：R541.4[医药卫生—心血管疾病] R856.5[医药卫生—内科学]