北京东北部山区人群嗜吞噬细胞无形体血清流行病学调查  

Seroepidemiological investigation on Anaplasma phagocytophilum in the population from northeast mountainous area of Beijing

作　　者：吕燕宁[1,2] 窦相峰[1] 陈丽娟[1] 孙玉兰[1] 张秀春[1] 关增智[1] 黎新宇[1] 王全意[1] 

机构地区：[1]北京市疾病预防控制中心/北京市预防医学研究中心,北京100013 [2]首都医科大学公共卫生学院,北京100069

出　　处：《中国人兽共患病学报》2016年第10期861-864,870,共5页Chinese Journal of Zoonoses

基　　金：国家科技重大专项(No.2012ZX10004215-003-001)~~

摘　　要：目的了解北京东北部山区人群嗜吞噬细胞无形体的感染状况,为制定相应的防控策略提供依据。方法在北京密云与怀柔区采集人群血清,采用间接免疫荧光法检测嗜吞噬细胞无形体IgG抗体,进行血清流行病学调查。结果 801份血清中嗜吞噬细胞无形体IgG抗体阳性者106份,阳性率13.23%,其中密云区为13.48%,怀柔区为12.70%,差异无统计学意义(P>0.05)。结论北京密云与怀柔区正常人群中均有嗜吞噬细胞无形体感染的存在,应加强人粒细胞无形体病的监测和防控工作。In order to study the epidemic state of Anaplasma phagocytophilurn infection in the population from the northeast districts of Beijing and to provide the basis for the prevention and control strategy of human granulocytic anaplasmosis （HGA）, a seroepidemiological investigation was carried out. Human serum samples were collected from the residents in Miyun and Huairou Districts of Beijing. Anaplasma phagocytophilum IgG antibody was tested by indirect immunofluorescence assay （IFA）. Results showed that 106 samples were positive of Anaplasma phagocytophilum IgG in total 801 samples, and the positive rate was 13.23%. The positive rate in Miyun district was 13.48%, and 12.70% in Huairou district. The difference was not statistically significant （P〉0.05）. In conclusion, the infection of Anaplasma phagocytophilum infection is prevalent in the normal population in Miyun and Huairou districts, and the surveillance, prevention and control of HGA should be strength- ened in these areas.

关 键 词：嗜吞噬细胞无形体 血清流行病学 间接免疫荧光法 

分 类 号：R183.5[医药卫生—流行病学]