3,3'-二氯-4,4'-二氨基二苯基甲烷的合成  

Synthesis of 3,3 '-Dichloro-4,4'-Diaminodiphenyl Methane

作　　者：胡长恺 

机构地区：[1]山东新时代药业,山东临沂273400

出　　处：《山东化工》2016年第21期12-14,18,共4页Shandong Chemical Industry

摘　　要：通过在硫酸水溶液和邻氯苯胺的体系中加入多聚甲醛制备了3,3'-二氯-4,4'-二氨基二苯基甲烷(MOCA)。考察了邻氯苯胺与多聚甲醛的物质的量比、加热反应时间、反应温度对3,3'-二氯-4,4'-二氨基二苯基甲烷(MOCA)合成产率的影响,通过熔点仪和红外光谱对产品进行了检测,发现当邻氯苯胺与多聚甲醛的物质的量比为2∶1、加热反应时间为150min、反应温度为80℃时制得的3,3'-二氯-4,4'-二氨基二苯基甲烷(MOCA)的产率最高,为90.1%。3,3 ＇-dichloro-4,4 ＇-diaminodiphenyl methane（ MOCA） is prepared by paraformaldehyde was added in an aqueous solution of sulfuric acid and o-chloroaniline system. Examine the molar ratio of o-chloroaniline with paraformaldehyde and heating the reaction time,reaction temperature of 3,3 ＇-dichloro-4,4 ＇-diaminodiphenyl methane（ MOCA） Synthesis yield,m. p. instrument and infrared spectrum of the product was tested and found that when o-chloroaniline with paraformaldehyde in the molar ratio is 2∶ 1,the the heated reaction time of 150 min,and the reaction temperature is 80 ℃ when the obtained 3,3 ＇-dichloro-4,4 ＇-diamino diphenyl methane（ MOCA） yield the highest maximum of 90. 1%.

关 键 词：多聚甲醛 3 3'-二氯-4 4'-二氨基二苯基甲烷 合成 产率 

分 类 号：TQ226.3[化学工程—有机化工]