Identification of antioxidant activity of two new aromatic ring butyrolactone derivatives from Dictamnus dasycarpus Turcz  

作　　者：GUO Li-Na PEI Yue-Hu XIE Fei-Xiang LIU Lei CONG Huan CUI Hong-Xia WANG Xiao-Li LI Wen-Jing JIAN Bai-Yu LIU Ji-Cheng 

机构地区：[1]School of Pharmacy, Qiqihar Medical University [2]School of Traditional Chinese Medicine, Shenyang Pharmaceutical University

出　　处：《Chinese Journal of Natural Medicines》2016年第11期876-880,共5页中国天然药物（英文版）

基　　金：supported by the Natural Science Foundation of Heilongjiang(No.D201207)

摘　　要：The present study carried out a phytochemical investigation on the root barks of Dictamnus dasycarpus Turcz, leading to the isolation and characterization of two new aromatic ring butyrolactone derivatives, dasycarpusphenol acid A(1) and dasycarpusphenol acid B(2). Their structures were elucidated by using spectroscopic techniques and HR-FAB-MS. Compounds 1 and 2 exhibited antioxidant activity, with their IC_(50) values being 28.95 and 41.76 mg·mL^(-1),respectively.The present study carried out a phytochemical investigation on the root barks ofDictamnus dasycarpus Turcz, leading to The isolation and characterization of two new aromatic ring butyrolactone derivatives, dasycarpusphenol acid A （1） and dasycarpusphenol acid B （2）. Their structures were elucidated by using spectroscopic techniques and HR-FAB-MS. Compounds 1 and 2 exhibited antioxidant activity, with their IC50 values being 28.95 and 41.76 mg·mL-1, respectively.

关 键 词：Dasycarpusphenol acid A Dasycarpusphenol acid B Dictamnus dasycarpus Antioxidant activity 

分 类 号：R284[医药卫生—中药学]