含氟类吡唑衍生物的合成方法研究进展  

Progress in the Synthetic Methods of Fluorine Pyrazole Derivatives

作　　者：徐保明[1] 华云涛 周宝晗[1] 陈坤[1] 

机构地区：[1]湖北工业大学材料与化学工程学院,武汉430068

出　　处：《农药》2016年第11期781-784,共4页Agrochemicals

基　　金：湖北省教育厅产学研重大项目(CXY2009A010);湖北省自然基金重点项目(2010CDA020)

摘　　要：吡唑类化合物具有良好的生物活性,其被广泛应用于农药领域。由于氟原子具有电子效应、阻碍效应和渗透效应等特殊的性质,把氟原子和含氟基团引入到具有生物活性的吡唑类化合物中,能大大地提高其生物活性。因此,含氟吡唑类化合物的合成一直受到国内外研究人员的关注。就含氟吡唑类化合物合成方法的研究进展进行了总结。Pyrazole derivatives are widely used in pesticides due to their good biological activities. As the fluorine atom has electronic effect, blocking effect and osmotic effect, introducing the fluorine atom or fluoride group to the pyrazole derivatives would greatly improve their biological activities. Therefore, the synthesis of fluorine pyrazole derivatives has attracted attention of the international researchers. The synthesis methods of the fluorine pyrazole derivatives were summarized.

关 键 词：含氟吡唑化合物 肼 炔烃 合成方法 

分 类 号：O626.21[理学—有机化学]