漂白土超早期干预与百草枯中毒对预后的影响  

Early use of bleaching earth in treatment of paraquat poisoning

作　　者：高夫海 田质光 赵义[1] 郭艳艳[1] 王广军[1] GAO Fuhai TIA N Zhiguang ZHAO Yi GUO Yanycm WANG Guangjun(Department of Occupation Poisoning,Xuzhou Tumor Hospital,Xuzhou,Jiangsu 221005, China)

机构地区：[1]徐州市肿瘤医院中毒职业病科,江苏徐州221005

出　　处：《职业卫生与应急救援》2016年第5期388-390,共3页Occupational Health and Emergency Rescue

基　　金：江苏省卫生计生委预防医学科研课题(编号:Y2015014)

摘　　要：目的观察院前第一时间给予漂白土灌服的百草枯(PQ)中毒患者的存活率。方法将2009—2015年420例PQ中毒患者分为两组,进行回顾性分析,常规组患者234例,在当地医院单纯清水洗胃,未给予漂白土灌服,转来我院后给予漂白土运用;早期干预组患者186例,当地医院清水洗胃后立即给予漂白土灌服,甘露醇导泻,转来我院后再次给予漂白土运用。观察两组的存活时间、存活率。结果早期干预组病死率32.3%,死者存活时间15 d,常规治疗组病死率45.3%,死者存活时间11 d,两组数据比较,差异均有统计学意义(P<0.05或0.01)。结论早期漂白土干预可提高PQ中毒的抢救成功率。加强基层医院PQ中毒急救培训,对提高PQ中毒患者存活率具有重要意义。Objective To observe the clinical effect of early use of bleaching earth in the treatment of paraquat（PQ） poisoning. Methods The clinical data of 420 PQ poisoning cases during 2009 to 2015 were analyzed. The patients were divided into two groups based on whether bleaching earth was used or not at early stage after the patients have their stomach pumped in the local hospitals before they were transferred into our hospital. The clinical fate of patients in these groups were compared after the known affecting factors, such as poisoning dose, were controlled. Results The fatality of 186 patients who received the early treatment of bleaching earth was 32.3% and the average survival time of these death cases was 15 d,while the fatality of 243 cases who did not received the early treatment of bleaching earth was 45.3% and the average survival time of these death cases was 11 d, and the differences were statistically significant （P 〈 0.05 or 0.01）. Conclusion These results indicated that super early use of bleaching earth could increase the success rate of rescuing PQ poisoning. It should be incorporated into regular measures in treatment of paraquat poisoning in the basic-level hospitals.

关 键 词：百草枯 漂白土 中毒 存活时间 

分 类 号：R139.3[医药卫生—劳动卫生]