116例胃肠道间质瘤的临床特点、MRI影像表现及病理分析  

Clinical Features,MRI Findings and Pathological Analysis of 116 Cases of Gastrointestinal Stromal Tumors

作　　者：金红花[1] 杨鹏平[2] 

机构地区：[1]武汉科技大学附属天佑医院放射科,湖北武汉430064 [2]武汉科技大学附属天佑医院急诊科,湖北武汉430064

出　　处：《中国CT和MRI杂志》2016年第12期90-92,共3页Chinese Journal of CT and MRI

摘　　要：目的探讨胃肠道间质瘤的临床、病理特点及MRI影像表现。方法收集我院2011年1月至2016年7月收治的116例胃肠道间质瘤患者作为研究对象进行回顾性分析,患者均行MRI检查,以病理结果为基准,总结患者临床特点及良性与恶性肿瘤MRI影像表现的差异。结果 116例患者中,14例为良性、29例为潜在恶性、73例为恶性。CD117阳性表达为98.3%、CD34阳性表达率为59.0%。14例良性病灶平扫示信号均匀22例,73例恶性患者信号不均,潜在恶性患者信号可均匀或不均匀。增强扫描良性多为均匀中等强化,恶性为不均匀强化。结论 GIST多见于50岁以上人群,患者多出现腹部胀痛不适、呕血与黑便等消化道出血症状,良性瘤病理表现为少见囊性变、出血、坏死,难见核分裂象;潜在恶性瘤可见囊性变或出血,但无肿瘤性坏死;恶性瘤可见囊性变、出血外、肿瘤性坏死,部分肌层浸润、血管浸润,核分裂象多在10个/50HPF以上。良性瘤的MRI平扫多为均匀信号;恶性为不均匀信号,增强扫描呈不均匀强化。Objective To investigate the clinical and pathological features and MRI findings of gastrointestinal stromal minors. Methods A total of 116 cases with gastrointestinal stromal tumors admitted in our hospital between January 2011 and July 2016 were selected as the study subjects and analyzed retrospectively. All patients underwent MRI examination. Based on the pathological results, the clinical features and differences in MRI findings between benign and malignant tumors were summarized.Results Among the 116 cases, 14 cases were benign, 29 were potential malignant, and 73 were malignant. The positive expression rate of CD 117 was 98.3% and of CD34 was 59.0%. For 14 cases with benign lesions, plain scan of 22 cases showed homogeneous signal while plain scan of 73 cases with malignant tumors showed inhomogeneous signal. Patients with potential malignant tumors showed both homogeneous and inhomogeneous signal. The enhanced scan of benign tumors showed homogeneous and moderate enhancement while of the malignant ones showed inhomogeneous enhancement. Conclusion GIST is more common in population over 50 years old. Most of the patients have abdo,ninal distension and pain, hematemesis, melena and other gastrointestinal bleeding symptonls. The pathological finding of benign tumors is little cystic degeneration, hemorrhage, necrosis and rare nuclear fission; Potential malignant tumors show cystic degeneration or hemorrhage, without minor necrosis. Malignant minor show cystic degeneration, hemorrhage, tumor necrosis, partial muscle invasion, blood vessel infiltration and nuclear fission more than 10/50HPF. The MRI plain scan of benign tumors shows more homogeneous signal while of malignant tumors shows inhomogeneous signal. The enhanced scan shows inhomogeneous enhancement.

关 键 词：胃肠道间质瘤 临床特点 MRI 影像表现 

分 类 号：R472.91[医药卫生—护理学]