四维面积应变评价不同左心室构型高血压患者的左心室功能  

The evaluation of left ventricular function in hypertension patients with different left ventricular configuration by four-demensional imaging area strain

作　　者：沈根松 徐丽萍 吴大利 

机构地区：[1]浙江省杭州市余杭中医院超声科,311106

出　　处：《中华医学超声杂志（电子版）》2016年第10期740-745,共6页Chinese Journal of Medical Ultrasound(Electronic Edition)

摘　　要：目的评价四维应变成像技术面积应变（4D-area strain）检测高血压不同左心室构型患者左心室收缩功能的价值。方法收集2015年2月至8月浙江省杭州市余杭中医院确诊的原发性高血压患者125例,根据Ganan分类法分为：正常构型组45例（A组）、向心性重构组25例（B组）、向心性肥厚组25例（C组）及离心性肥厚组30例（D组）。另选取本院体检中心40名健康人作为健康对照组（N组）。采用4D-area strain检测各组与健康对照组常规左心室收缩功能指标与整体面积应变（GAS）、节段面积应变（RAS）值,进行相互比较。组间整体面积应变与对应的节段面积应变比较采用多样本均数方差分析,多个均数间的两两比较采用LSD-t检验。结果 （1）常规心功能：A、B、C、D及N组左心室舒张末期容积（EDV）、心搏量（SV）及心输出量（CO）测值比较,差异均无统计学意义（F=0.679、3.829、0.600,P均〉0.05）,收缩末期容积（ESV）、射血分数（EF）、球形指数（Spl）、舒张末期重量（EDMass）测值比较,差异均有统计学意义（F=3.829、6.596、2.653、2.604,P均〈0.05）;D组ESV测值与N、A、B、C组比较,差异有统计学意义（t=2.011、2.244、3.685、2.278,P均〈0.05）;B组ESV测值与N组比较,差异有统计学意义（t=2.170,P〈0.05）;B组EF测值与N、A、D组比较,差异有统计学意义（t=2.452、3.514、4.949,P均〈0.05）;D组EF测值与N、C组比较,差异有统计学意义（t=2.849、3.486,P均〈0.05）;D组Sp I测值与N、A、B、C组比较,差异有统计学意义（t=2.854、2.941、3.200、2.979,P均〈0.05）;C组EDMass测值与N、A组比较,差异有统计学意义（t=2.170、2.087,P均〈0.05）;D组EDMass测值与A、B、N组比较,差异有统计学意义（t=2.668、2.081、3.762,P均〈0.05）。（2）GAS：A、B、C、D各组与N组GAS测值比较,差异均有统计学意义（t=7.950、7.361、8.959、11.277,P均〈0.01）,且随左心室Objective To evaluate the left ventricular systolic function of different patients with hypertension by Four-demensional imaging area strain（4D-area strain）. Methods Totally 125 hypertension patients and 40 normal subjects（group N） were enrolled. According to Ganan classification, hypertension patients were classified into normal geometry（groups A, n=45）, concentric remodeling（group B, n=25）, concentric hypertrophy（group C, n=25） and eccentric hypertrophy（group D, n=30）. Parameters of left ventricular systolic function, including global area strain（GAS）, regional area strain（RAS） and left ventricular end-diastolic volume（EDV）, end-systolic volume（ESV）, stroke volume（SV）, cardiac output（CO）, ejection fraction（EF）, spherical index（Spl）, end-diastolic weight（EDMass） were analyzed. Results There was no statistically significant difference among thegroups A, B, C, D, and N in left ventricular EDV, SV and CO（F=0.679, 3.829, 0.600, P 0.05）. There were statistically significant differences among ESV, EF, Spl and EDMass（F=3.829, 6.596, 2.653, 6.596, P 0.05）. There were statistically significant differences among ESV of group D and that of groups N, A, B and C（t=2.011, 2.244, 3.685 and 2.244, P 0.05）. There was statistically significant difference among ESV of group B with that of group N（t=2.170, P 0.05）. There were statistically significant differences among EF of group B with that of groups N, A and D（t=2.452, 3.514 and 2.452, P 0.05）. There were statistically significant differences among EF of group D with that of groups N and C（t=2.849 and 3.486, P 0.05）, There were statistically significant differences among Sp I of group D with that of groups N, A, B and C（t=2.854, 2.941, 3.200 and 2.941, P 0.05）. There were statistically significant differences among EDMass of group C with that of groups N and A（t=2.170 and 2.087, P 0.05）. There were statistically significant differences among EDMass of group D with that of groups A, B and

关 键 词：超声检查 心室功能 左 高血压 

分 类 号：R544.1[医药卫生—心血管疾病]