超声造影技术对老年颈动脉粥样硬化斑块的稳定性分析  

Analysis of the stability of carotid atherosclerotic plaque in elderly patients by contrastenhanced ultrasound

作　　者：陈建梅[1] 王秋霜[1] 黄党生[1] 张丽伟[1] 王淑华[1] 姬冬冬[1] 马永江[1] 郭家瑞[1] 

机构地区：[1]解放军总医院第一附属医院心内科,北京100039

出　　处：《中国医学装备》2016年第7期64-67,共4页China Medical Equipment

基　　金：解放军总医院科技创新苗圃基金(14KMM26)"超声造影评价不同他汀药物对糖尿病患者颈动脉斑块内新生血管的影响"

摘　　要：目的:探讨超声造影技术对老年颈动脉粥样硬化斑块的稳定性分析的意义。方法:选取26例颈动脉粥样硬化斑块的老年患者,予以超声造影检查及CT检查,统计超声检查对各类型斑块的检出数量,并与CT对各类型斑块检出数量进行比较,以CT检出数量为标准,计算超声检出率。依据超声检查的斑块数量,计算超声造影对各类型斑块造影增强率,分析超声造影技术对斑块类型的敏感性,判断其对动脉硬化斑块稳定性鉴别作用。结果:1超声检查对斑块检出数量与CT检测相比无显著差异;2超声造影技术对软斑块造影增强率最高,可达94.59%,其次为混合斑块75.00%,对钙化斑块造影增强率最低,仅为17.65%。结论:超声检查对于颈动脉粥样硬化斑块检出率与CT相比无显著差异,超声造影对于软斑块及混合斑块造影增强率高,可有效对斑块进行定性分析,判断其稳定性,对防止脑血管疾病发生有重要意义。Objective： To investigate the analysis of the stability of carotid atherosclerotic plaque in elderly patients by contrast-enhanced ultrasound. Methods： 26 elderly patients with carotid atherosclerotic plaque from the First Affiliated Hospital of PLA General Hospital were selected and got ultrasound contrast examination and CT examination. The numbers of types of plaques by contrast enhanced ultrasound and CT were compared and the detectable rate in contrast enhanced ultrasound was computed. According to the number of patches of ultrasound, the contrast enhancement rate of each type of plaque was calculated and the high sensitivity of ultrasound contrast technology to determine the type of plaque was analyze, in order to determine its role in the stability of atherosclerotic plaque. Results： The four types of plaque detected by contrast enhanced ultrasound and CT were no significant difference （Fisher exact probability, P=0.144〉0.05）. The enhancement rate of contrast enhanced ultrasound in soft plaque was the highest, up to 94.59%. The mixed plaque with 75% was the higher. And the enhancement rate of the calcified plaque was the lowest, only 17.65%. Conclusion：There was no significant difference between ultrasonography and CT for carotid atherosclerotic plaque detection rate. The contrast enhancement rate of contrast-enhanced ultrasonography for soft plaque and mixed plaque is high. It is effective to analyze plaque qualitatively and determine its stability, and is significant to prevent the incidence of cerebral vascular disease.

关 键 词：超声造影技术 颈动脉粥样硬化斑块 稳定性分析 X射线计算机断层扫描仪 

分 类 号：R445.1[医药卫生—影像医学与核医学]