基于石墨烯复合材料的5-羟色胺电化学传感器  

Electrochemical Sensor of 5-hydroxytryptamine Based on Graphene Nanocomposites

作　　者：谢丽清[1] 徐飘扬[1] 刘艺婷[1] 王善善[1] 高宁宁[1] 刘泉宏[1] 高飞[1,2] XIE Li-qing XU Piao--yang LIU Yi-ting WANG Shan-shan GAO Ning-ning LIU Quan-hong GAO Fei(College of Chemistry and Environment, Minnan Normal University, Zhangzhou, Fujian 363000, China Fujian Provincial Key Laboratory of Modem Analytical Science and Separation Technology, Minnan Normal University, Zhangzhou, Fujian 363000, China)

机构地区：[1]闽南师范大学化学与环境学院,福建漳州363000 [2]闽南师范大学福建省现代分离分析科学与技术重点实验室,福建漳州363000

出　　处：《闽南师范大学学报（自然科学版）》2016年第2期44-53,共10页Journal of Minnan Normal University：Natural Science

基　　金：国家自然科学基金(21275127;21301143);福建省自然科学基金项目(2011J01059);福建省高校科研专项项目(JK2011032)

摘　　要：以水热法制备了聚苯胺/还原氧化石墨烯复合材料,将其超声分散于乙醇溶液中,滴涂在聚对氨基苯磺酸修饰玻碳电极表面,得到聚苯胺/还原氧化石墨烯/聚对氨基苯磺酸修饰玻碳电极.采用循环伏安法考察了5-羟色胺（5-HT）在修饰电极上的电化学行为.实验结果表明该电极对5-HT的氧化反应过程表现出良好的催化活性.最佳条件下,氧化峰电流与5-HT的浓度在0.10~100.0μmol/L范围呈良好线性关系,其线性方程为I_p（μA）=-0.0419C（μmol/L）-0.4171（R=0.996）,检出限为0.032μmol/L.当抗坏血酸和多巴胺的浓度增大到5-HT的50倍时,5-HT峰电流几乎不受影响,表明该修饰电极对5-HT检测具有良好的选择性.A nanocomposite of polyaniline/reduced graphene oxide （PANI-rGO） was synthesized by hydrotherrnal method, and then the hybrid material of PANI-rGO was dispersed in ethanol by ultrasonication method. The dispersion was dropped on the surface of glassy carbon electrode pre-modified with poly（p-aminobenzene sulfonic acid） （Pp-ABSMGCE）. The electrochemical behaviors of 5-hydroxytryptamine （5-HT） on the fabricated electrode were studied by cyclic voltammetry. It was found that the fabricated electrode had favorable catalytic activity toward oxidation of 5-HT. Under the optimum conditions, the oxidation peak currents were good linearly correlated with the concentration of 5-HT in the range from 0.1 txmol/L to 100.0μmol/L, with a linear regression equation of Ip （μA） = -0.0419C （μmoFL） - 0.4171 （R= 0.996） and a detection limit of 0.032μol/L （S/N=3）. When the concentration of interfering substances such as ascorbie acid and dopamine increased to 50 times higher than 5-HT, the peak current signals were almost not affected, showing that the fabricated electrode had fine selectivity for the detection of 5-HT.

关 键 词：聚苯胺 石墨烯 聚对氨基苯磺酸 5-羟色胺 电化学 

分 类 号：O611.6[理学—无机化学] O657.1[理学—化学]