2型糖尿病患者血镁水平与颈动脉内膜中层厚度的相关性研究  

Correlation between blood magnesium level and carotid artery intima-media thickness in patients with type 2 diabetes

作　　者：姬晓苑 高艳霞[2] 寇博[3] 郭璐[1] 

机构地区：[1]宁夏石嘴山市第一人民医院内分泌科,宁夏石嘴山753200 [2]宁夏医科大学总医院内分泌科,宁夏银川750004 [3]宁夏石嘴山市第一人民医院骨科,宁夏石嘴山753200

出　　处：《宁夏医学杂志》2016年第11期1019-1021,共3页Ningxia Medical Journal

摘　　要：目的探讨2型糖尿病患者血镁水平与颈动脉内膜中层厚度的相关性。方法收集2型糖尿病患者200例,根据颈动脉内膜中层厚度分为正常组、增厚组和斑块组,记录血镁、体重指数、血脂、血压、血糖、胰岛素抵抗指数等临床指标,比较3组间各个指标的差异。结果斑块组和增厚组的血镁显著低于正常组(P<0.05),血镁与劲动脉内膜中层厚度呈负相关;Logistic回归分析提示血镁是颈动脉血管病变的保护因素,胰岛素抵抗指数、吸烟、低密度脂蛋白是颈动脉血管病变的危险因素。结论 2型糖尿病患者血镁与颈动脉内膜中层厚度呈负相关性,低血镁可能是糖尿病大血管病变的危险因素。Objective To explore the correlation between blood magnesium levels and carotid intima -media thickness in pa- tients with type 2 diabetes. Methods 200 patients with type 2 diabetes were divided into the normal group, the thickened group and plaque group according to the carotid intima - media thickness. The clinical indicator including blood magnesium, body mass index, blood adipose, blood pressure, and blood glucose and insulin resistance indicator were recorded. Compared the indicator among three groups. Results Blood magnesium of plaque group and thickened group was significantly lower than normal group （P 〈 0.05 ）. And blood mag- nesium was negatively correlated with carotid intima- media thickness. Logistic regression analysis showed that blood magnesium was a protective factor for vascular lesions of carotid artery. Insulin resistance index, smoking,low density lipoprotein were risk factors for vas- cular lesions of carotid artery. Conclusion Blood magnesium is negatively correlate with carotid intima - media thickness in patients with type 2 diabetes. And low blood magnesium may be a risk factor for diabetes vascular lesions.

关 键 词：血镁 颈动脉内膜中层厚度 动脉粥样硬化 

分 类 号：R587.1[医药卫生—内分泌]