乳腺增生发病机制与治疗及其动物模型制备的研究进展  

Research Advances in Pathogenesis of Mammary Gland Hyperplasia and Medication and Its Establishment of Animal Model

作　　者：张忠元[1] 程荷珍[1] 

机构地区：[1]武汉科技大学附属天佑医院药剂科,武汉430064

出　　处：《抗感染药学》2016年第5期966-969,共4页Anti-infection Pharmacy

摘　　要：乳腺增生病为女性人群常见的以周期性乳房疼痛为主要特征的非炎症、非肿瘤的慢性乳房疾病。目前认为雌激素与孕激素的比例失调为HMG的主要病因。近年来,其发病率呈逐年上升趋势,此疾病临床主要采用激素、三苯氧胺、乳癖散结胶囊和乳癖消等药物治疗。综述HMG的发病机制与治疗药物以及HMG动物模型的制备文献,并对其研究进展作了分析。The disease of mammary gland hyperplasia is a non-cancer chronic breast disease, which commonly causes women periodic breast pain as its main characteristics of the inflammation. The imbalance of estrogen and pro- gesterone is the primary reason of hyperplasia of mammary glands now. In recent years, there has been an upward trend in the incidence, and clinical treatment of this disease is mainly the use of hormone, tamoxifen, breast fights capsule and other drugs. The literature of the pathogenesis of mammary gland hyperplasia and therapeutic drugs, and establishing an- imal models of hyperplasia of mammary glands were reviewed, and their research progresses were analyzed.

关 键 词：乳腺增生 动物模型 发病机制 研究进展 

分 类 号：R696[医药卫生—泌尿科学]